Publications by authors named "Felice Cardillo-Piccolino"
Article Synopsis
- The study investigated choroidal vascular responses in chronic central serous chorioretinopathy (CSCR) patients using optical coherence tomography (OCT) during temporary blood pressure increases from physical stress.
- It compared CSCR patients with age-matched healthy individuals, measuring parameters like mean ocular perfusion pressure (MOPP) and choroidal thickness at rest and during hand-grip exercises.
- Results showed CSCR patients had higher MOPP and choroidal thickness compared to controls, but unlike healthy subjects, they did not exhibit a vasoconstrictive response to stress, indicating possible impairment in their choroidal blood flow regulation.
Article Synopsis
- The study investigates whether the thickness of anterior scleral substantia propria (ASSP) can predict responses to half-dose photodynamic therapy (PDT) in patients with central serous chorioretinopathy (CSCR) over a 3-month period.
- Conducted in multiple hospitals in Italy and Switzerland, the research involved 109 Caucasian patients, focusing on clinical data and optical coherence tomography measurements to categorize different CSCR phenotypes and their ASSP thickness.
- Results indicated that thicker ASSP is associated with complex CSCR and a higher likelihood of PDT non-responsiveness, emphasizing its potential role in understanding CSCR's severity and treatment outcomes.
Purpose: To evaluate whether frequent vigorous physical activity (PA) is significantly associated with active central serous chorioretinopathy (CSCR) and may represent a risk factor for CSCR.
Design: Case-control study.
Methods: This was a multicenter study.
Purpose: To visualize photoreceptors using the Spectralis High Magnification Module (HMM) in a case of central serous chorioretinopathy (CSCR) and to correlate the findings with those of optical coherence tomography (OCT) and optical coherence tomography angiography (OCT-A).
Observations: A 35-year-old Caucasian male presenting with chronic CSCR in the left eye was examined using HMM, OCT and OCT-A. The photoreceptors mosaic was assessed both in diseased and apparently uninvolved areas.
Purpose: To study structural and functional outcomes of cystoid macular degeneration (CMD) in chronic central serous chorioretinopathy (CSCR).
Methods: This retrospective study included 26 eyes having chronic CSCR with CMD who underwent either observation, photodynamic therapy (PDT), micropulse laser, or eplerenone therapy. Various optical coherence tomography parameters were analyzed at baseline and 1 year.
Article Synopsis
- - Choroidal rupture is an eye condition caused by trauma, leading to damage in the retinal layers, which can severely impact vision, especially if the macula is involved or there are other underlying health issues.
- - It presents as a whitish/yellowish crescent-shaped lesion seen during an eye exam, and various imaging techniques can help evaluate the severity and complications.
- - While there's no specific treatment for choroidal rupture itself, associated complications may require medical intervention, and the text discusses the condition's underlying mechanisms, imaging results, and management strategies for these complications.
The study aims to analyze the changes produced by half-dose photodynamic therapy (HD-PDT) in the choroid of eyes with chronic central serous chorioretinopathy (CSC) applying the binarization method to spectral domain optical coherence tomography (SDOCT) and OCT Angiography (OCTA) images. SDOCT and OCTA were performed before, one hour, one week, and one month after HD-PDT. Binarization with a modified Niblack method and analysis by ImageJ were applied.
View Article and Find Full Text PDFAims: To perform an automated functional assessment of retinal and choroidal microvasculature in eyes with low-grade diabetic retinopathy (DR) using optical coherence tomography angiography (OCT-A) and to identify potential perfusion changes in case of early vascular damage.
Methods: This is an observational, case-control study of consecutive diabetic patients with level 20 DR severity scale score and age-matched healthy subjects. A prototypal OCT-angiography was used to obtain the OCT-angiograms of the superficial capillary plexus (SCP), deep capillary plexus (DCP) and choriocapillaris (CC) layer.
Purpose: To compare optical coherence tomography-angiography (OCT-A) performed during physical exercise (stress OCT-A) to the basal examination (rest OCT-A) in the imaging of choroidal neovascularization (CNV) in patients with chronic central serous chorioretinopathy (CSCR).
Design: Prospective, cohort study.
Methods: This multicenter study included 29 consecutive patients with chronic CSCR and flat irregular pigment epithelium detachments (FIPEDs).
Central serous chorioretinopathy (CSC) is a common cause of central vision loss, primarily affecting men 20-60 years of age. To date, no consensus has been reached regarding the classification of CSC, and a wide variety of interventions have been proposed, reflecting the controversy associated with treating this disease. The recent publication of appropriately powered randomised controlled trials such as the PLACE trial, as well as large retrospective, non-randomised treatment studies regarding the treatment of CSC suggest the feasibility of a more evidence-based approach when considering treatment options.
View Article and Find Full Text PDFRetinal Vascular Reactivity in Central Serous Chorioretinopathy.
Invest Ophthalmol Vis Sci
September 2018
Purpose: To investigate the retinal vascular response to the isometric exercise in patients with central serous chorioretinopathy (CSCR) by using optical coherence tomography angiography (OCT-A).
Methods: This was a multicenter case-control study including 35 CSCR patients and 25 age-matched healthy controls. All subjects underwent macular OCT-A scans in resting conditions and during a handgrip isometric exercise.
Choroidal Vascular Reactivity in Central Serous Chorioretinopathy.
Invest Ophthalmol Vis Sci
August 2018
Purpose: To investigate by optical coherence tomography angiography (OCT-A) the choroidal vascular response to experimentally increased blood pressure in patients with central serous chorioretinopathy (CSCR).
Methods: For this multicenter, observational, case-control study, we enrolled 35 patients with an established diagnose of CSCR and 25 age-matched healthy controls. All subjects underwent a handgrip isometric exercise to obtain elevation of blood pressure (BP).
Optical coherence tomography angiography is one of the biggest advances in ophthalmic imaging. It enables a depth-resolved assessment of the retinal and choroidal blood flow, far exceeding the levels of detail commonly obtained with dye angiographies. One of the first applications of optical coherence tomography angiography was in detecting the presence of choroidal neovascularization in age-related macular degeneration and establishing its position in relation to the retinal pigmented epithelium and Bruch's membrane, and thereby classifying the CNV as type 1, type 2, type 3, or mixed lesions.
View Article and Find Full Text PDFPurpose: To find possible correlations between the morphologic macular changes revealed by fundus autofluorescence (FAF) and the functional parameters such as visual acuity and retinal sensitivity in patients with chronic central serous chorioretinopathy (CSC).
Design: Prospective, cross-sectional study.
Methods: Forty-six eyes (39 consecutive patients) with chronic CSC were studied with FAF and microperimetry (MP).
Purpose: To compare the efficacy and safety of half-fluence vs half-dose photodynamic therapy (PDT) in chronic central serous chorioretinopathy (CSC).
Design: Multicenter retrospective comparison study.
Methods: Retrospective review of 56 patients affected by chronic CSC, including 28 patients (31 eyes) who received half-fluence PDT and 28 patients (29 eyes) who received half-dose PDT.
Effect of ocular contusion in a patient with chronic central serous chorioretinopathy.
Retin Cases Brief Rep
November 2014
Purpose: We report the effect of ocular contusion in a patient with chronic central serous chorioretinopathy and posterior cystoid retinal degeneration.
Methods: A 56-year-old man who being followed for recurrent-chronic central serous chorioretinopathy presented with blurred vision in the left eye 6 days after contusion of the eye by a soccer ball. Previously, the left eye had received multiple laser treatments in the papillomacular region resulting in a large chorioretinal scar.
Purpose: To report a case of exudative age-related macular degeneration (AMD) complicated by vitreomacular traction and treated with intravitreal bevacizumab.
Methods: Interventional case report. An 83-year-old man presented with exudative AMD with subretinal fluid.
Background: Fundus autofluorescence is already used to evaluate inflammatory disorders affecting the chorioretinal interface. We investigated the autofluorescence characteristics of two cases of serpiginous choroiditis (SC) during recurrent acute episodes, and followed them until their resolution. We compared the autofluorescence findings with those obtained with other imaging techniques.
View Article and Find Full Text PDFPurpose: To identify factors associated with the development of posterior cystoid retinal degeneration (PCRD) in central serous chorioretinopathy (CSC).
Methods: The authors retrospectively studied 51 eyes of 51 patients with chronic CSC and subretinal or intraretinal exudation documented by optical coherence tomography (OCT), and evaluated the association of hypertension, systemic use of corticosteroids, duration of symptoms, subretinal fibrosis, and large laser scars with the development of PCRD.
Results: Twenty-four eyes (47%) had PCRD and 27 eyes (53%) had serous macular detachment without cystoid retinal changes.
Purpose: To study the pattern of cystoid retinal changes in the posterior fundi of eyes with chronic central serous chorioretinopathy (CSC) using optical coherence tomography (OCT).
Methods: We retrospectively studied 34 eyes with chronic CSC and cystoid retinal changes at the posterior pole documented by OCT. We analyzed the distribution of cystoid retinal changes with respect to the fovea and chorioretinal lesions.
Purpose: To investigate the effects of photodynamic therapy (PDT) on subfoveal choroidal neovascularization (CNV) secondary to reticular pattern dystrophy (RPD) of the retinal pigment epithelium.
Design: Open-label, prospective, interventional case series.
Methods: Thirteen eyes diagnosed with subfoveal CNV associated with RPD were considered.
Purpose: To evaluate the correlation between optical coherence tomographic evaluations of foveal thickness and anatomical changes within the fovea and visual acuity in patients who have unilateral resolved central serous chorioretinopathy.
Methods: A retrospective review of cases of unilateral resolved central serous chorioretinopathy imaged with high-resolution optical coherence tomography was performed. The foveal thickness of the involved eye was normalized by dividing its thickness by that of the uninvolved fellow eye.