Predicting risk of peripartum blood transfusion during vaginal and cesarean delivery: A risk prediction model.

Objective: The objective of this study is to develop a model that will help predict the risk of blood transfusion using information available prior to delivery.

Study Design: The study is a secondary analysis of the Consortium on Safe Labor registry. Women who had a delivery from 2002 to 2008 were included.

Methadone diminishes neuroinflammation and disease severity in EAE through modulating T cell function.

Methadone is known to exert modulatory effects on the immune system. We investigated the potential effects of methadone on infiltration of inflammatory cells into the spinal cord, as well as the proliferative and cytokine responses of T cells in MOG(35-55)-induced experimental autoimmune encephalomyelitis in mice. Methadone significantly suppressed clinical signs of the disease and level of inflammatory cytokines (p<0.