Management for children and adolescents with overweight and obesity: a recommendations mapping.

Background: Childhood obesity is a global public health issue, and the status of clinical practice guidelines (CPGs) as instruction manuals for the management of childhood obesity remains unclear. This study aims to identify and apprise the methodological and reporting quality of CPGs focused on childhood obesity and provide an overview of key recommendations.

Methods: Databases and websites reporting guidelines were searched from January, 2018 to September, 2023.

Construction and characterization of a cuproptosis- and immune checkpoint-based LncRNAs signature for breast cancer risk stratification.

Background: Cuproptosis is the most recently identified form of cell death, and copper homeostasis is an important cancer therapeutic target. However, the therapeutic benefits of cuproptosis-targeted treatment in BRCA remain undetermined. This study utilized LncRNAs linked to cuproptosis genes and immune checkpoint genes to generate a BRCA predictive signature.

Performance of adenosine deaminase in detecting paediatric pleural tuberculosis: a systematic review and meta-analysis.

Background: Paediatric pleural tuberculosis (TB) is a paucibacillary disease, which increases the difficulty of examination. We aimed to assess the performance of pleural fluid adenosine deaminase (ADA) in the detection of paediatric pleural TB.

Methods: PubMed, Web of Science Core Collection, Embase and Cochrane Library databases were searched up to 20 December 2021.

The landscape of DNA methylation in asthma: a data mining and validation.

Human asthma is caused by interactions between a range of genetic and environmental factors. However, the specific pathogenesis of asthma remains controversial. This study explored the contribution of DNA methylation to asthma using computer learning methods.