Publications by authors named "Feisal Yamani"
Am J Surg Pathol
June 2020
Article Synopsis
- Giant cell tumor of bone (GCT) is a benign but locally aggressive tumor primarily made up of mononuclear and giant cells, with H3F3A gene mutations found in 96% of cases, indicated by immunohistochemistry.
- GCT can have woven bone and cartilage matrix, which can complicate diagnosis, especially when distinguishing it from more aggressive tumors like osteosarcoma.
- In a study of 17 GCT cases with cartilage matrix, most patients had successful outcomes post-surgery, though some experienced recurrences, highlighting the importance of accurate diagnosis to avoid unnecessary treatments.
