Publications by authors named "Feipeng Gong"
Article Synopsis
- The study examines the pharmacological effects of volatile components from Atractylodis Rhizoma and how processing affects these components, particularly in terms of reducing dryness and increasing efficacy.
- Using HS-GC-MS technology, the researchers identified a total of 87 volatile components across various processed forms of Atractylodis Rhizoma, revealing significant differences in composition based on processing methods.
- The analysis highlighted 28 key components that showed significant changes post-processing, with 11 specific volatile compounds, such as α-pinene and D-limonene, increasing notably after treatment.
Article Synopsis
- - The study investigates a simplified surgical method, modified posterior osteotomy, to treat elderly patients with osteoporotic vertebral collapse and delayed neurological dysfunction, aiming to improve clinical outcomes.
- - A total of 12 patients with an average age of 65.5 years participated, and metrics such as pain levels and disability were significantly improved post-surgery, with a notable decrease in the visual analogue scale (VAS) score and Oswestry Disability Index (ODI).
- - Results indicate that while the procedure had a significant average operative time of 3.7 hours and blood loss of approximately 483.3 ml, the overall clinical efficacy and safety of the modified technique showed promising outcomes for this patient demographic.
The unique pharmaceutical methods for the processing of botanical drugs according to the theory of traditional Chinese medicine (TCM) affect clinical syndrome differentiation and treatment. The objective of this study was to comprehensively elucidate the principles and mechanisms of an herbal processing method by investigating the alterations in the metabolites of Rhizoma Atractylodis Macrocephalae (AMR) processed by Aurantii Fructus Immaturus (AFI) decoction and to determine how these changes enhance the efficacy of aqueous extracts in treating functional dyspepsia (FD). A qualitative analysis of AMR before and after processing was conducted using UPLC-Q-TOF-MS/MS, and HPLC was employed for quantitative analysis.
View Article and Find Full Text PDFArticle Synopsis
- - Plasmacytoma is a rare condition involving plasma cell growth in bones or soft tissues, with types including solitary bone and extramedullary plasmacytomas; it can occur alongside chronic conditions like osteomyelitis.
- - A 47-year-old man with a history of chronic osteomyelitis experienced ulceration in his tibia, leading to imaging tests that revealed dead bone and inflammation, prompting surgical intervention.
- - Post-surgery, the diagnosis was confirmed as plasmacytoma, and the patient received successful radiotherapy; this case emphasizes the need for careful monitoring of chronic osteomyelitis for possible plasmacytoma development.
Article Synopsis
- The study investigates the use of platelet-rich plasma (PRP) as a treatment for severe wounds with exposed tendons, addressing a significant clinical issue in wound healing.
- A total of 12 patients with refractory wounds were treated with PRP injections following debridement, showing a healing time of about 23 days and significant improvements in scar assessment scores.
- Results indicated that PRP therapy not only sped up healing and reduced inflammation but also improved tissue quality, with high patient satisfaction reported during follow-up.
Research Progress on the Mechanism of Reducing Toxicity and Increasing the Efficacy of Sini Decoction Compatibility.
Chem Pharm Bull (Tokyo)
December 2022
Sini Decoction (SND) is the main prescription for treating Shaoyin disease in Zhang Zhongjing's Treatise on Typhoid diseases in Han Dynasty. It is composed of Aconitum carmichaeli Debeaux, Glycyrrhiza uralensis Fisch ex DC and Zingiber officinale Roscoe. It has the effects of warming middle-jiao to dispel cold and revive the yang for resuscitation.
View Article and Find Full Text PDFBackground: No review or meta-analysis exists to elucidate the efficacy and safety of quadratus lumborum block (QLB) on the pain intensity, opioid requirement, and mobilization in patients undergoing hip surgery. This systematic review and meta-analysis of randomized controlled trials were designed to compare QLB with no block or placebo (without other nerve/plexus blocks) for patients undergoing hip surgery.
Methods: Two individual researchers conducted the platform searches on the PubMed, Cochrane Library, and Embase databases from inception to June 12, 2021.
Exploring the Potential Mechanism of Chuanxiong Rhizoma Treatment for Migraine Based on Systems Pharmacology.
Evid Based Complement Alternat Med
December 2021
Migraine is a disease whose aetiology and mechanism are not yet clear. Chuanxiong Rhizoma (CR) is employed in traditional Chinese medicine (TCM) to treat various disorders. CR is effective for migraine, but its active compounds, drug targets, and exact molecular mechanism remain unclear.
View Article and Find Full Text PDFExploration of Ziziphi Spinosae Semen in Treating Insomnia Based on Network Pharmacology Strategy.
Evid Based Complement Alternat Med
October 2021
Ziziphi Spinosae Semen (ZSS) is a common natural medicine used to treat insomnia, and to show clearly its method of action, we managed and did an in-depth discussion. Network pharmacology research is very suitable for the analysis of multiple components, multiple targets, and multiple pathways of Traditional Chinese Medicine (TCM). According to the relevant theory, we first carefully collected and screened the active ingredients in ZSS and received 11 active ingredients that may work.
View Article and Find Full Text PDFAccording to the treatment records of Yang deficiency syndrome (YDS) with characteristic decoction pieces of lateral root of -Yinfupian (YF) in traditional Chinese medicine prepare school, known as "Jianchangbang". The aim of this study was to investigate differences in the composition and therapeutic mechanism of the unprocessed lateral root of (ULRA) and its processed product (YF). Ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry and orthogonal partial least squares discriminant analysis method were used to determine and screen the main components of ULRA and YF.
View Article and Find Full Text PDFObjective: To investigate the relationship between the cardiotonic activity of Fuzi (Radix Aconiti Lateralis Preparata, RALP) and its fingerprint determined by liquid chromatography-mass spectrometry (LC-MS).
Methods: First, the fingerprints of six processed products of RALP were established by high performance liquid chromatography quadrupole time-of-flight mass spectrometry (HPLC-Q-TOF-MS) followed by analysis of the principal component of the relative peak area of its common peaks. Next, the scores of the first five principal components were used as input for an artificial neural network (ANN).
Article Synopsis
- A 22-year-old man suffered a comminuted patellar fracture after a traffic accident, which made it difficult to repair due to the complexity of the fracture.
- The treatment involved using multiple 3D-printed guide plates to assist in the reduction and fixation of the fracture.
- Over a 2-year follow-up, the patient experienced good recovery without significant limitations in knee function, highlighting the effectiveness of this innovative technique in surgical treatment.
Article Synopsis
- Circular RNAs (circRNAs) like circ_0000285 play a significant role in the progression of diseases, including osteosarcoma (OS), but their functions are not completely understood.
- Researchers found that circ_0000285 expression was higher in OS tissues and that knocking it down can reduce OS growth through various assays.
- The study revealed that circ_0000285 influences OS cell behavior by interacting with miR-409-3p and the protein IGFBP3, suggesting that targeting circ_0000285 could be a therapeutic strategy for OS.
Primitive neuroectodermal tumours (PNETs) are rare malignant small round cell tumours. Notably, despite widespread reports of PNET in multiple parts of the body, it is extremely rare in the pelvis. Here, a rare case of giant PNET of the pelvis, that was treated with surgical intervention comprising hemipelvectomy and amputation, is reported.
View Article and Find Full Text PDFObjective: As a new minimally invasive surgery developed in recent years, the procedure of endoscope-assisted transforaminal lumbar interbody fusion (TLIF) has not been well described. We herein describe a patient with lumbar disc herniation who underwent direct foraminoplasty and thorough decompression using a self-designed endoscopic trephine in endoscope-assisted TLIF at L4–5.
Methods: A 57-year-old man presented with a 3-month history of low back and right leg pain.
Comments on: "Mini hook plate fixation for thumb ulnar collateral ligament avulsion fracture: A technical report" of Shingo Komura, Akihiro Hirakawa, Kyohei Ishizuka, Yasuharu Matsushita, Haruhiko Akiyama, published in Orthop Traumatol Surg Res 2019;105(3):429-433.
Orthop Traumatol Surg Res
October 2019
Five-pointed star lattice sutures for fixation of patella transverse fractures: a clinical study.
Eur J Orthop Surg Traumatol
January 2019
Introduction: Fixation of displaced patella fractures with metal implants may be associated with implant failure, post-operative pain, and high re-operation rate. This study reports preliminary clinical results of using five-pointed star lattice sutures for the management of patella transverse fractures.
Methods: A five-pointed star lattice suture configuration was produced intraoperatively, and 25 patients with patella transverse fractures were treated with this newly designed sutures fixation.
[EFFECTS OF BONE MARROW MESENCHYMAL STEM CELLS TRANSPLANTATION FOR TREATING RAT SPINAL CORD INJURY AND CYTOKINE EXPRESSION AT INJURY SITES].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
March 2016
Objective: To investigate the effects of bone marrow mesenchymal stem cells (BMSCs) transplantation for treating spinal cord injury (SCI) in rat and the cytokine expression changes in the local injury tissues.
Methods: BMSCs were separated from Sprague Dawley (SD) rat and cultured with the whole bone marrow culture method. rAd-EGFP was used to transfect the 5th generation BMSCs for green fluorescent protein (GFP) label.
Objective: To explore a operative approach and its effect to the central protrusion of lumbar intervertebral disc.
Methods: From February 1999 to December 2005,34 patients with central protrusion of lumbar intervertebral disc were treated with an improved operative procedure. The study involved 25 males and 9 females with an average of 46.