Child sleep problems mediate prospective associations between fathers' parenting stress and child blood glucose levels.

The present study examined the role of first-time fathers' parenting stress during infancy in relation to children's mean blood glucose via glycated hemoglobin (HbA1c) levels during middle childhood while also exploring the mediating role of child sleep problems in this association. A total of 306 fathers self-reported on parenting stress when their children were 10 months old (49% of girls). Fathers also reported on child sleep problems when their children were 24 months old.

TEAD1-Mediated Trans-Differentiation of Vascular Smooth Muscle Cells into Fibroblast-Like Cells Contributes to the Stabilization and Repair of Disrupted Atherosclerotic Plaques.

Atherosclerotic plaque rupture mainly contributes to acute coronary syndrome (ACS). Insufficient repair of these plaques leads to thrombosis and subsequent ACS. Central to this process is the modulation of vascular smooth muscle cells (VSMCs) phenotypes, emphasizing their pivotal role in atherosclerotic plaque stability and healing post-disruption.

Adaptation of a couples intervention to promote coparenting and reduce hazardous drinking during transition to parenthood.

Introduction: Hazardous drinking by fathers poses a significant risk for negative family interactions and child outcomes. The transition to parenthood may be a time when expectant parents are potentially motivated for health behavior change, suggesting that implementing preventive interventions during this period may be particularly effective. This article provides an overview of the rationale for an innovative prevention strategy incorporating alcohol-use intervention with a family-focused program.

Parental warmth and parent-child conflict among U.S. Latinx families in middle childhood.

Grounded in family systems theory and using latent profile analysis, the present study examined (a) patterns of parent-child warmth and parent-child conflict within multiple dyads (mother-older child, mother-younger child, father-older child, father-younger child) among 305 U.S. Latinx families with fifth graders ( = 10.

Clinical Validation of Deep Learning for Segmentation of Multiple Dental Features in Periapical Radiographs.

Periapical radiographs are routinely used in dental practice for diagnosis and treatment planning purposes. However, they often suffer from artifacts, distortions, and superimpositions, which can lead to potential misinterpretations. Thus, an automated detection system is required to overcome these challenges.

Long-term effects of changes in coparenting quality during the COVID-19 pandemic.

This study examines changes in coparenting quality during the initial stage of the COVID-19 pandemic on long-term parent, child, and family well-being. Although there is clear evidence that the COVID-19 pandemic negatively impacted families, less is known about family resilience factors that could mitigate this impact. Understanding whether positive coparenting quality is a protective factor during crises is important for promoting parent, child, and family well-being.

Cascading Effects of the Family Context in Adolescence: Implications for Young Adult Antisocial Behavior and Intergenerational Transmission of Risk.

Inspired by the tremendous impact of Robert McMahon's career, this study evaluated an intergenerational cascade model in which young adult conduct problems may serve as a risk pathway linking generation 1 (G1) parenting and family climate in adolescence with generation 2 parenting quality and family climate with their children (G2-G3). Our sample included 396 parents (M = 28.3; 70% women; child M = 3.

Automatic feature segmentation in dental panoramic radiographs.

Objective: The purpose of the present study was to verify the diagnostic performance of an AI system for the automatic detection of teeth, caries, implants, restorations, and fixed prosthesis on panoramic radiography.

Methods: This is a cross-sectional study. A dataset comprising 1000 panoramic radiographs collected from 500 adult patients was analyzed by an AI system and compared with annotations provided by two oral and maxillofacial radiologists.

Family functioning and child internalizing and externalizing problems: A 16-wave longitudinal study during the COVID-19 pandemic.

This study explored young children's mental health trajectories during the pandemic (May 2020 to April 2021) as well as associations with family functioning (i.e., cohesion, conflict, chaos, and routines) using data reported by 204 parents (children M 5.

Evolution of the Moral Lexicon.

Morality is central to social well-being and cognition, and moral lexicon is a key device for human communication of moral concepts and experiences. How was the moral lexicon formed? We explore this open question and hypothesize that words evolved to take on abstract moral meanings from concrete and grounded experiences. We test this hypothesis by analyzing semantic change and formation of over 800 words from the English Moral Foundations Dictionary and the Historical Thesaurus of English over the past hundreds of years.

Trends in patient characteristics and mortality among Medicare patients diagnosed with peripheral artery disease.

Introduction: Peripheral artery disease (PAD) is a well-described risk factor for mortality, but few studies have examined secular trends in mortality over time for patients with PAD. We characterized trends in mortality in patients with PAD in recent years among Medicare patients.

Methods: We used Medicare claims to identify patients with a new diagnosis code for PAD between January 1, 2006 and December 31, 2018 using International Classification of Diseases (ICD) diagnosis codes.

Trajectories of psychological distress for Australian fathers parenting a child on the autism spectrum: Evidence from early childhood to adolescence.

This study explores the mental health journey of fathers with children on the autism spectrum. Little is known about mental health over time for these fathers. This research spans six-timepoints from when children were aged 4 to 14 years, to track fathers' mental health.

Protective Effect of Parental Monitoring on Early-to-Mid Adolescents Displaying High-Level and Increasing Aggressive Behavior.

Studies that distinguish parental monitoring (parent-driven behaviors) from parental knowledge often fail to find protective effects of monitoring on adolescent behavior problems. To answer whether parental monitoring is more strongly associated with adolescent behavior problems among adolescents who may need it most, this study applied group-based trajectory modeling to change in early- to mid-adolescent aggressive behavior problems and examined associations between parental monitoring with different subgroups. Three latent groups of adolescents were found: Low Aggression, Medium-Increasing Aggression, and High-Increasing Aggression.

Association between tissue loss type and amputation risk among Medicare patients with concomitant diabetes and peripheral arterial disease.

Objective: Prior studies have described risk factors associated with amputation in patients with concomitant diabetes and peripheral arterial disease (DM/PAD). However, the association between the severity and extent of tissue loss type and amputation risk remains less well-described. We aimed to quantify the role of different tissue loss types in amputation risk among patients with DM/PAD, in the context of demographic, preventive, and socioeconomic factors.

Measurement invariance of the Coparenting Relationship Scale (CRS) across 10 countries.

The purpose of this study was to assess the factor structure and the measurement invariance of the Coparenting Relationship Scale (CRS) across 10 countries based on the seven-factor coparenting model (i.e., Coparenting Agreement, Coparenting Closeness, Exposure to Conflict, Coparenting Support, Endorsement of Partner's Parenting; Division of Labor) proposed by Feinberg (2003).

Couple relationship functioning and social adjustment during the transition to parenthood among fathers with a history of maltreatment.

Study of fathers has gained significant traction over recent decades. However, the experience for men over the transition to parenthood remains focused on high-socioeconomic and socially advantaged fathers. Researchers have yet to thoroughly investigate how fathers may uniquely experience this transition period with a history of childhood maltreatment, given that childhood abuse is known to impact several components of development and relationship functioning into adulthood.

Injectable Self-Oxygenating Cardio-Protective and Tissue Adhesive Silk-Based Hydrogel for Alleviating Ischemia After Mi Injury.

Myocardial infarction (MI) is a significant cardiovascular disease that restricts blood flow, resulting in massive cell death and leading to stiff and noncontractile fibrotic scar tissue formation. Recently, sustained oxygen release in the MI area has shown regeneration ability; however, improving its therapeutic efficiency for regenerative medicine remains challenging. Here, a combinatorial strategy for cardiac repair by developing cardioprotective and oxygenating hybrid hydrogels that locally sustain the release of stromal cell-derived factor-1 alpha (SDF) and oxygen for simultaneous activation of neovascularization at the infarct area is presented.

miR-369-3p ameliorates diabetes-associated atherosclerosis by regulating macrophage succinate-GPR91 signalling.

Aims: Diabetes leads to dysregulated macrophage immunometabolism, contributing to accelerated atherosclerosis progression. Identifying critical factors to restore metabolic alterations and promote resolution of inflammation remains an unmet goal. MicroRNAs orchestrate multiple signalling events in macrophages, yet their therapeutic potential in diabetes-associated atherosclerosis remains unclear.

MicroRNA-181 in cardiovascular disease: Emerging biomarkers and therapeutic targets.

Cardiovascular disease (CVD) is the leading cause of death worldwide. MicroRNAs (MiRNAs) have attracted considerable attention for their roles in several cardiovascular disease states, including both the physiological and pathological processes. In this review, we will briefly describe microRNA-181 (miR-181) transcription and regulation and summarize recent findings on the roles of miR-181 family members as biomarkers or therapeutic targets in different cardiovascular-related conditions, including atherosclerosis, myocardial infarction, hypertension, and heart failure.

Examining profiles of convergence and divergence in reports of parental warmth: Links to adolescent developmental problems.

Parental warmth during the transition from childhood to adolescence is a key protective factor against a host of adolescent problems, including substance use, maladjustment, and diminished well-being. Moreover, adolescents and parents often disagree in their perceptions of parenting quality, and these discrepancies may confer risk for problem outcomes. The current study applies latent profile analysis to a sample of 687 mother-father-6th grade adolescent triads to identify patterns of adolescent-parent convergence and divergence in perceptions of parental warmth.