Advances in Stigmasterol on its anti-tumor effect and mechanism of action.

Stigmasterol is a phytosterol derived from multiple herbaceous plants such as herbs, soybean and tobacco, and it has received much attention for its various pharmacological effects including anti-inflammation, anti-diabetes, anti-oxidization, and lowering blood cholesterol. Multiple studies have revealed that stigmasterol holds promise as a potentially beneficial therapeutic agent for malignant tumors because of its significant anti-tumor bioactivity. It is reported that stigmasterol has anti-tumor effect in a variety of malignancies (e.

Rapid hydrothermal synthesis of hierarchical ZSM-5/beta composite zeolites.

An innovative hydrothermal method has been successfully applied to the synthesis of hierarchical ZSM-5/beta composite zeolites with different mass ratios. Firstly, the ZSM-5 zeolites were coated with amorphous silica and aluminum species by a spray drying process. Then, the precursor powder was hydrothermally crystallized for only 1-2 days with the addition of tetraethyl ammonium hydroxide (TEAOH).

Relations of COVID-19-Related Stressors and Social Support With Chinese College Students' Psychological Response During the COVID-19 Pandemic.

This study examines the main and interactive relations of stressors and social support with Chinese college students' psychological symptoms (e.g., anxiety, depression) during the COVID-19 pandemic.

Enhancing Catalytic Activity and Selectivity by Plasmon-Induced Hot Carriers.

Plasmon-assisted chemical transformation holds great potential for solar energy conversion. However, simultaneous enhancement of reactivity and selectivity is still challenging and the mechanism remains mysterious. Herein, we elucidate the localized surface plasmon resonance (LSPR)-induced principles underlying the enhanced activity (∼70%) and selectivity of photoelectrocatalytic redox of nitrobenzene (NB) on Au nanoparticles.

Bimetallic gold/silver nanoclusters as a fluorescent probe for detection of methotrexate and doxorubicin in serum.

New bimetallic gold/silver nanoclusters (NCs) are reported that display strong blue fluorescence with excitation/emission maxima at 370/455 nm, decay times of around 14 ns for the main components, and a quantum yield of around 20%. The NCs were synthesized by using L-tryptophan (L-Trp) as the template to react with tetrachloroauric acid and silver nitrate at 120 °C for 4 h in a one-pot reaction. Their fluorescence is around 5 times stronger than that of pure gold nanoclusters.

Cataluminescence sensor for highly sensitive and selective detection of iso-butanol.

In this paper, a gaseous sensor was described for detection of iso-butanol on the basis of its strong cataluminescence (CTL) emission on nano-MgO surface. The sensor showed high sensitivity and specificity to iso-butanol with response time less than 1 s and recovery time less than 18 s. A good linearly relationship between CTL intensity and the concentration of iso-butanol was observed in the range of 7.

Development of a Colloidal Gold-Based Immunochromatographic Strip for Rapid Detection of H7N9 Influenza Viruses.

Both high- and low-pathogenic H7N9 influenza A virus (IAV) infections have been found in human and poultry in China, and most human cases are related to contact with infected poultry. It is necessary to develop a rapid and simple method to detect H7N9 IAV in poultry. In this study, 13 monoclonal antibodies (McAbs) against the H7N9 IAV hemagglutinin were developed, and three critical amino acid epitopes (198, 227, 235) were identified based on the reactivity of these variant and wild-type strains with the McAbs.

Development of a multiplex probe combination-based one-step real-time reverse transcription-PCR for NA subtype typing of avian influenza virus.

Nine influenza virus neuraminidase (NA) subtypes have been identified in poultry and wild birds. Few methods are available for rapid and simple NA subtyping. Here we developed a multiplex probe combination-based one-step real-time reverse transcriptase PCR (rRT-PCR) to detect nine avian influenza virus NA subtypes.

Characteristics of two highly pathogenic avian influenza H5N8 viruses with different pathogenicity in mice.

Novel reassortant influenza A (H5N8) viruses are becoming a potential threat not only to the poultry industry but also to public health. Many molecular markers for pathogenicity in mammalian hosts have been identified in other H5 subtype avian influenza viruses (AIVs). However, the pathogenicity of H5N8 AIVs to mammals remains unclear.