Interwoven Porous Pristine Cobalt-Based Metal-Organic Framework as an Efficient Photocatalyst for CO Reduction.

As a desired utilization of the conversion of CO into valuable carbon fuel production under solar energy, it remains challenging due to the lack of efficient catalysts. Herein, a 3D interpenetrating metal-organic framework of [Co(Tipa)(HCOO)(HO)]·HO (Co-Tipa) with 1D open channel is solvothermally synthesized using a semi-flexible ligand (Tipa = tri-(4-(1H-imidazol-1-yl)-phenyl)amine). The tridentate bridge ligand-oriented periodicity Co-Tipa MOF is combined with ruthenium-based photosensitizers under mild reaction conditions to form an efficient nonhomogeneous co-catalyst for photocatalytic CO reduction reaction (CORR).

The influence of different extraction indications on the morphological changes in the maxillary sinus: A retrospective cohort study.

Aims: The comprehensive effects of maxillary posterior tooth extraction on the maxillary sinus (MS) morphology remain to be thoroughly elucidated. This retrospective cohort study aimed at evaluating the influence of different extraction indications on the morphological changes in the MS by utilizing cone-beam computed tomography (CBCT).

Methods: One hundred and seventy-eight of maxillary posterior tooth extractions underwent CBCT scans before and after extraction using 3D Slicer software.

Pillar-Supported 2D Layered MOFs with Abundant Active-Site Distributions for High-Performance Alkaline Supercapacitors.

The development of two-dimensional (2D) layered metal-organic frameworks (MOFs) through precise molecular-level design and synthesis has emerged as a prominent research endeavor. However, the utilization of MOFs in their pristine form as electrodes for supercapacitors poses a significant challenge due to their limited tolerance in alkaline environments. To address these issues, we have developed Co- and Cu-based pillar-layered MOFs by regulating the structure of their inner layers through introducing an alkaline N-containing "pillar" to enhance the performance of alkaline supercapacitor electrodes.

Clinical relevance of distolingual roots and periodontal status in mandibular first molars: a cross-sectional study employing CBCT analysis.

: Distolingual root of the permanent mandibular first molar (PMFM-DLR) has been frequently reported, which may complicate the treatment of periodontitis. This study aimed to assess the morphological features of PMFM-DLR and investigate the correlation between the morphological features of PMFM-DLR and periodontal status in patients with Eastern Chinese ethnic background. : A total of 836 cone beam computed tomography (CBCT) images with 1497 mandibular first molars were analyzed to observe the prevalence of PMFM-DLR at the patients and tooth levels in Eastern China.

Mechanism Research and Application for Ginsenosides in the Treatment of Hepatocellular Carcinoma.

Ginsenosides, the main active pharmacological ingredients of ginseng, have been widely used for the treatment of numerous carcinomas. Hepatocellular carcinoma (HCC) is 3 leading malignant tumor in terms of mortality worldwide. Accumulating evidence indicates that ginsenosides play a vital role in the prevention and treatment of HCC.

Exploration for cobalt/nitrogen-doped catalyst to creatinine degradation via peroxymonosulfate activation: toxicity evaluation, statistical modeling, and mechanisms study.

Developing multifunctional catalysts applied in diversiform modes via advanced oxidation processes (AOPs) is a promising and attractive approach for organic pollution degradation. Herein, a novel hollow bamboo-like structural cobalt/nitrogen-doped carbonized material (CoC/N) was employed as a catalyst for AOPs, in which CoC/N was prepared in situ through calcining a Co-based coordination polymer. When CoC/N was utilized as a peroxymonosulfate (PMS) activator, the catalyst stood out prominent activities for effective CA oxidation.

Combined FOLFOX4 with all-trans retinoic acid versus FOLFOX4 with placebo in treatment of advanced hepatocellular carcinoma with extrahepatic metastasis: a randomized, double-blind comparative study.

The majority of hepatocellular carcinoma (HCC) cases are diagnosed at an advanced stage. Currently, there are only a few therapeutic methods available for patients with advanced HCC and extrahepatic metastasis (EHM). Systemic chemotherapy, such as FOLFOX4 (infusions of fluorouracil, leucovorin, and oxaliplatin), has been reported for treating advanced HCC with EHM, but its effectiveness is very poor.

Camrelizumab plus gemcitabine and oxaliplatin for the treatment of advanced intrahepatic cholangiocarcinoma: a bi-centric observational retrospective study.

Background: Immune checkpoint inhibitor (ICI), coupled with systemic chemotherapy, may enhance the clinical benefit of cancer by potentiating antitumor immunity, but its efficacy and safety are not clear in advanced intrahepatic cholangiocarcinoma (ICC). This study aims to assess the efficacy and safety of camrelizumab plus gemcitabine and oxaliplatin (GEMOX) for the treatment of advanced ICC in the real world.

Methods: Advanced ICC patients receiving at least one session of camrelizumab plus GEMOX combination treatment from March 2020 to February 2022 at two high-volume centers were considered eligible.

[C(NH)NHNO][C(NH)](NO): A Mixed Organic Cationic Hybrid Nitrate with an Unprecedented Nonlinear-Optical-Active Unit.

We herein report a mixed organic cationic hybrid nitrate, namely, [C(NH)NHNO][C(NH)](NO) (). It was successfully achieved via combining three different planar groups: [(C(NH)NHNO], C(NH), and NO. First-principles calculations confirm that the [(C(NH)NHNO] group is an excellent cationic nonlinear-optical (NLO)-active unit.

Network pharmacology-based analysis of Resinacein S against non-alcoholic fatty liver disease by modulating lipid metabolism.

Background: is reportedly the best source of traditional natural bioactive constituents. Ganoderma triterpenoids (GTs) have been verified as an alternative adjuvant for treating leukemia, cancer, hepatitis and diabetes. One of the major triterpenoids, Resinacein S, has been found to regulate lipid metabolism and mitochondrial biogenesis.

Transarterial chemoembolization plus immune checkpoint inhibitor as postoperative adjuvant therapy for hepatocellular carcinoma with portal vein tumor thrombus: A multicenter cohort study.

Purpose: This study aimed to assess the efficacy and safety of postoperative adjuvant transarterial chemoembolization (PA-TACE) plus immune checkpoint inhibitor (ICI) for hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT).

Patients And Methods: This study was conducted on three centers from June 2018 to December 2020. Patients were divided into the PA-TACE (n = 48) and PA-TACE plus ICI groups (n = 42).

C(NH)(IO)(HIO)(HIO)(HIO)·3HO: An Unprecedented Asymmetric Guanidinium Polyiodate with a Strong Second-Harmonic-Generation Response and a Wide Band Gap.

Herein, we report an unprecedented asymmetric guanidinium polyiodate, namely, C(NH)(IO)(HIO)(HIO)(HIO)·3HO (). The title compound was obtained via the hybridization of polyiodate anions and planar π-conjugated C(NH); meanwhile, its strong second-harmonic-generation (SHG) response (2.1 × KDP, where KDP = KHPO) and wide band gap (3.

Central nitrogen vacancies in polymeric carbon nitride for boosted photocatalytic HO production.

Polymeric carbon nitride (PCN) with vacancies usually exhibits distinguished mass transfer efficiency, outstanding carrier kinetics and excellent photoactivity. Previous studies have revealed the effect of edge vacancies in heptazine units of PCN; however, the roles of central nitrogen vacancies are scarcely investigated. Herein, central nitrogen vacancies polymeric carbon nitride (PCN-NV) is rationally prepared for photocatalytic HO production with a rate of 25.

Na(CO)(HBO)(HO)·HBO: the first borate-squarate with strong SHG response obtained by superior synergy.

We herein report the first sodium borate-squarate, namely, Na(CO)(HBO)(HO)·HBO (1). It has been successfully synthesized introducing the planar π-conjugated (CO) into a borate system. Compound 1 exhibits a strong second-harmonic-generation (SHG) response (2.

Cuproptosis-related lncRNAs predict the clinical outcome and immune characteristics of hepatocellular carcinoma.

Cuproptosis, as a novel copper-dependent and non-apoptotic form of cell death, is induced by aggregation of lipoylated mitochondrial proteins and the instability of Fe-S cluster proteins. However, the role of cuproptosis-related long noncoding RNAs (CRLncRNAs) in hepatocellular carcinoma (HCC) has not been clearly elucidated. In this study, we identified and characterized cuproptosis-related lncRNAs in HCC.

A novel chemotherapy strategy for advanced hepatocellular carcinoma: a multicenter retrospective study.

Background: Chemotherapy is a common treatment for advanced hepatocellular carcinoma, but the effect is not satisfactory. The study aimed to retrospectively evaluate the effects of adding all-trans-retinoic acid (ATRA) to infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) for advanced hepatocellular carcinoma (HCC).

Methods: We extracted the data of patients with advanced HCC who underwent systemic chemotherapy using FOLFOX4 or ATRA plus FOLFOX4 at the Eastern Hepatobiliary Surgery Hospital, First Hospital of Jilin University, and Zhejiang Sian International Hospital and retrospectively compared for overall survival.

KCHO(HO): A Promising UV Nonlinear-Optical Material with Large Birefringence Based on a π-Conjugated (CHO) Group.

In order to meet the growing needs for the laser technology and optics industries, the goal is to find suitable fundamental building blocks with large nonlinear-optical (NLO) coefficients and birefringence for an excellent-performance NLO or birefringent system. Via preliminary investigations and calculations, it has been found that the planar π-conjugated group (CHO) possesses large polarizability anisotropy (δ) and hyperpolarizability (β), comparable to well-known groups such as (BO), (CNO), etc. Herein, we report a new alkali-metal 3,5-dicarboxybenzoate, KCHO(HO) (KHBTC), which crystallized in the acentric space group 2.

Mechanistic Insights into the Mechanism of Inhibitor Selectivity toward the Dark Kinase STK17B against Its High Homology STK17A.

As a member of the death-associated protein kinase (DAPK) family, STK17B plays an important role in the regulation of cellular apoptosis and has been considered as a promising drug target for hepatocellular carcinoma. However, the highly conserved ATP-binding site of protein kinases represents a challenge to design selective inhibitors for a specific DAPK isoform. In this study, molecular docking, multiple large-scale molecular dynamics (MD) simulations, and binding free energy calculations were performed to decipher the molecular mechanism of the binding selectivity of PKIS43 toward STK17B against its high homology STK17A.

Coal-based ultrathin N-doped carbon nanosheets synthesized by molten-salt method for high-performance lithium-ion batteries.

Coal is a typical fossil fuel and it is also a natural carbon material, therefore, converting it to functional carbon materials is an effective way to enhance the economic advantages of coal. Here, ultrathin N-doped carbon nanosheets were prepared from low-cost coal via a handy and green molten-salt method, which shown excellent performance for lithium-ion batteries (LIBs). The formation mechanism of ultrathin nanosheets was studied in detail.

Noncentrosymmetric (CHN)(HPO)(HPO)·4HO and Centrosymmetric (CHN)SO·2HO: Exploration of Acentric Structure by Combining Planar and Tetrahedral Motifs via Hydrogen Bonds.

The combination of organic and inorganic nonlinear active units to obtain organic-inorganic hybrid materials has been proved to be a very effective method to obtain nonlinear optical (NLO) materials with excellent properties. Herein we reported two hybrid melamine-based compounds, namely, acentric (CHN)(HPO)(HPO)·4HO () and centrosymmetric (CHN)SO·2HO (), which were synthesized via facile solvent evaporation method. Compound features a three-dimensional (3D) network structure composed of [(HPO)(HPO)(HO)] layers which are further linked with [(CHN)] layers via hydrogen bonds.

Water and mildew proof SiO & ZnO/silica sol superhydrophobic composite coating on a circuit board.

In order to improve the waterproof and mildew resistance of electronic equipment, a superhydrophobic coating was prepared on a circuit board. First, hexadecyl trimethoxysilane was used to modify the nano silica and nano zinc oxide particles, and then the modified nanoparticles were mixed with the silica sol. Then the superhydrophobic coating was prepared on the surface of the printed circuit board by a spraying process.