Combined Metabolome and Transcriptome Analysis Revealed the Accumulation of Anthocyanins in Grape Berry ( L.) under High-Temperature Stress.

In grape ( L.) cultivation, high temperatures (HTs) usually reduce the accumulation of anthocyanins. In order to elucidate the regulatory mechanism of anthocyanin biosynthesis under high-temperature environments, we investigated the effects of HT stress at veraison (5% coloring of grape ears) on fruit coloration and anthocyanin biosynthesis in 'Summer Black' (XH) and 'Flame seedless' (FL) grapevines.

Transcriptomic and physiological analyses reveal different grape varieties response to high temperature stress.

High temperatures affect grape yield and quality. Grapes can develop thermotolerance under extreme temperature stress. However, little is known about the changes in transcription that occur because of high-temperature stress.

Development and validation of a predictive score for venous thromboembolism in newly diagnosed non-small cell lung cancer.

Introduction: The risk of venous thromboembolism (VTE) varies among tumour types, and different cancer type-specific risks for VTE prediction remain undefined. We aimed to establish a prediction model for non-small lung cancer (NSCLC)-associated VTE.

Materials And Methods: We analysed data from a prospective cohort of patients with newly diagnosed NSCLC.

The complete chloroplast genome sequence of × V.

× is a tetraploid grape, a Franco-american species. This study first published the complete chloroplast genome of × was assembled. The chloroplast genome is 160928 bp in length, including a large single copy region (89,148 bp), a small single-copy region (19,072 bp) and a pair of inverted repeats of 26,354 bp.

Association of ALK rearrangement and risk of venous thromboembolism in patients with non-small cell lung cancer: A prospective cohort study.

Background: Isolated reports are inconsistent regarding the risk of venous thromboembolism (VTE) in patients with anaplastic lymphoma kinase (ALK) rearranged non-small cell lung cancer (NSCLC). This study examined whether ALK rearrangement could have an influence on VTE in a prospective cohort.

Methods: In a cohort of 836 consecutive patients with NSCLC, patients with epidermal growth factor receptor (EGFR) or kitten rat sarcoma (KRAS) mutations were ruled out for VTE interference.

Association between oncogenic status and risk of venous thromboembolism in patients with non-small cell lung cancer.

Background: Preclinical data suggest that oncogene (EGFR and KRAS) events regulate tumor procoagulant activity. However, few studies have prospectively investigated the clinical relevance between the presence of EGFR or KRAS mutations and occurrence of venous thromboembolism(VTE) in patients with non-small cell lung cancer (NSCLC).

Methods: A total of 605 Chinese patients with newly diagnosed NSCLC were included and were followed for a maximum period of 4.

[A technique for the vein extraction from the susceptibility weighted imaging of the brain].

This paper studies the vein extraction technique based on the susceptibility weighted imaging (SWI) and introduced an improved self-adaptive threshold method based on the vessel enhancing diffusion. The approach employs the combination indicator of the local gray character, the global gray character and the tubular information of the vein. It first applies the vessel enhancing diffusion filter to enhance the continuity of the vein, increases the detection rate of tiny vein and suppresses the nucleus areas.