Publications by authors named "Feibin Zhu"
Article Synopsis
- The study investigates the use of exosomes from human bone marrow mesenchymal stem cells (hBMSC-Exos) to treat keloid formation by examining their effects on keloid fibroblasts (KFs) and in animal models.
- hBMSC-Exos were found to inhibit KF proliferation, migration, and invasion while promoting their apoptosis and reducing fibrosis-related protein expression.
- The mechanism revealed that hBMSC-Exos deliver a long non-coding RNA (MEG3) that stabilizes the TP53 protein, which in turn promotes MCM5 transcription, influencing KF activity.
High-risk human papillomavirus (HR-HPV) infection is a major risk factor for the initiation and progression of cervical cancer (CC). This study aimed to explore the role of histone deacetylase 6 (HDAC6) in HPV-positive CC and the molecules implicated. Differentially expressed genes between HPV-positive and HPV-negative tissues, and differentially expressed microRNAs (miRNAs) in cells after HDAC6 downregulation were identified using microarray analyses.
View Article and Find Full Text PDFExogenous substance P accelerates wound healing in diabetes, but the mechanism remains poorly understood. Here, we established a rat model by intraperitoneally injecting streptozotocin. Four wounds (1.
View Article and Find Full Text PDFObjective: To observe the effect of sensory neuropeptide substance P combined with epidermal stem cells (ESC) on wound healing and nerve regeneration in diabetic rats.
Methods: ESC that had been isolated from SD rats were identified and cultured in vitro, and they were inoculated onto nourishing layer of amniotic membrane to construct amniotic membrane-ESC. Four full-thickness skin wounds were produced on the back of each of 48 diabetic rats.