Behavior Changes in Quinpirole Obsessive-Compulsive Disorder Rats Treated with 6-Hydroxydopamine and the Corresponding Dopaminergic Compulsive Loop Mechanism.

Background: Recent studies suggest that the anterior limb of the internal capsule may be an area of convergence for multiple compulsion loops. In this study, the role of different dopaminergic compulsion loops in the mechanism of obsessive-compulsive disorder (OCD) was investigated by selectively damaging dopaminergic neurons or fibers in the corresponding targets with 6-hydroxydopamine (6-OHDA) and depicting the anatomical map of various compulsion loops located in the anterior limb of the internal capsule.

Methods: A total of 52 male Sprague Dawley (SD) rats were exposed to either saline (1 mL/kg, NS group, n = 6) or quinpirole (QNP, dopamine D2-agonist, 0.

Anterior capsulotomy and accumbensotomy of obsessive-compulsive disorder with obsessional slowness: a case report.

Unlabelled: Obsessional slowness (OS) is characterized by a syndrome of extreme slowness in doing ordinary, day-to-day activities. Several scholars regarded OS as secondary to obsessive compulsive disorder (OCD). Therefore, it is commonly thought to be the consequence of extensive rituals and has been paid minimal attention in its own right.

Hollow Mo/MoS Nanoreactors with Tunable Built-in Electric Fields for Sustainable Hydrogen Production.

Constructing built-in electric field (BIEF) in heterojunction catalyst is an effective way to optimize adsorption/desorption of reaction intermediates, while its precise tailor to achieve efficient bifunctional electrocatalysis remains great challenge. Herein, the hollow Mo/MoS nanoreactors with tunable BIEFs are elaborately prepared to simultaneously promote hydrogen evolution reaction (HER) and urea oxidation reaction (UOR) for sustainable hydrogen production. The BIEF induced by sulfur vacancies can be modulated from 0.

Synthesis of in-plane MoC/MoO heterostructures by a novel spatial-confined partial oxidation approach for enhanced TEA sensing.

In-plane heterostructures exhibit extraordinary chemical and electron transfer properties, which have received remarkable research attention. However, the synthesis of an in-plane MoC/MoO heterostructure has been rarely reported, and the deep investigation of the effect of its fine structure on reactivity is of great significance. Notably, the in-plane heterostructures endow the material with abundant grain boundaries, which facilitate the formation of surface acid sites and active oxygen species, thus contributing to the sensing performance.

Engineering of in-plane SnS-SnO nanosheets heterostructures for enhanced HS sensing.

In-plane heterostructures has attracted considerable interest due to exceptional electron transport properties, high specific surface area, and abundant active sites. However, synthesis of in-plane SnS-SnO heterostructures are rarely reported, and the deep investigation of the fine structure on reactivity is of great significance. Here, we propose partial in-situ oxidation strategy to construct the in-plane SnS-SnO heterostructures and the surface properties, the ratio of two components can be finely tuned by precisely adjusting the treatment temperature.

Oxygen Vacancy Enabled Electronic Structure Engineering of Pt-WO Nanosheets toward Highly Efficient BTEX Sensing.

A Pt nanoparticle-immobilized WO material is a promising candidate for catalytic reactions, and the surface and electronic structure can strongly affect the performance. However, the effect of the intrinsic oxygen vacancy of WO on the d-band structure of Pt and the synergistic effect of Pt and the WO matrix on reaction performance are still ambiguous, which greatly hinders the design of advanced materials. Herein, Pt-decorated WO nanosheets with different electronic metal-support interactions are successfully prepared by finely tuning the oxygen vacancy structure of WO nanosheets.

A Sustainable Route to Ruthenium Phosphide (RuP)/Ru Heterostructures with Electron-Shuttling of Interfacial Ru for Efficient Hydrogen Evolution.

Ruthenium (Ru) is a promising electrocatalyst for the hydrogen evolution reaction (HER), despite suffering from low activity in non-acidic conditions due to the high kinetic energy barrier of HO dissociation. Herein, the synthesis of carbon nanosheet-supported RuP/Ru heterostructures (RuP/Ru@CNS) from a natural polysaccharide is reported and demonstrates its behavior as an effective HER electrocatalyst in non-acidic conditions. The RuP/Ru@CNS exhibits low overpotential (106 mV at 200 mA·cm) in alkaline electrolyte, exceeding most reported Ru-based electrocatalysts.

Trifunctional L-Cysteine Assisted Construction of MoO/MoS/C Nanoarchitecture Toward High-Rate Sodium Storage.

The volume collapse and slow kinetics reaction of anode materials are two key issues for sodium ion batteries (SIBs). Herein, an "embryo" strategy is proposed for synthesis of nanorod-embedded MoO/MoS/C network nanoarchitecture as anode for SIBs with high-rate performance. Interestingly, L-cysteine which plays triple roles including sulfur source, reductant, and carbon source can be utilized to produce the sulfur vacancy-enriched heterostructure.

Enabling Ultrafine Ru Nanoparticles with Tunable Electronic Structures via a Double-Shell Hollow Interlayer Confinement Strategy toward Enhanced Hydrogen Evolution Reaction Performance.

Engineering of the catalysts' structural stability and electronic structure could enable high-throughput H production over electrocatalytic water splitting. Herein, a double-shell interlayer confinement strategy is proposed to modulate the spatial position of Ru nanoparticles in hollow carbon nanoreactors for achieving tunable sizes and electronic structures toward enhanced H evolution. Specifically, the Ru can be anchored in either the inner layer (Ru-DSC-I) or the external shell (Ru-DSC-E) of double-shell nanoreactors, and the size of Ru is reduced from 2.

Universal Sub-Nanoreactor Strategy for Synthesis of Yolk-Shell MoS Supported Single Atom Electrocatalysts toward Robust Hydrogen Evolution Reaction.

The coordination structure determines the electrocatalytic performances of single atom catalysts (SACs), while it remains a challenge to precisely regulate their spatial location and coordination environment. Herein, we report a universal sub-nanoreactor strategy for synthesis of yolk-shell MoS supported single atom electrocatalysts with dual-anchored microenvironment of vacancy-enriched MoS and intercalation carbon toward robust hydrogen-evolution reaction. Theoretical calculations reveal that the "E-Lock" and "E-Channel" are conducive to stabilize and activate metal single atoms.

Use of differential stimulation of the nucleus accumbens and anterior limb of the internal capsule to improve outcomes of obsessive-compulsive disorder.

Objective: Personalized stimulation is key to optimizing the outcomes of deep brain stimulation (DBS) for refractory obsessive-compulsive disorder (OCD). However, the contacts in a single conventional electrode cannot be programmed independently, which may affect the therapeutic efficacy of DBS for OCD. Therefore, a novel designed electrode and implantable pulse generator (IPG) that could achieve differential stimulation parameters for different contacts was implanted into the nucleus accumbens (NAc) and anterior limb of the internal capsule (ALIC) of a cohort of patients with OCD.

Ultra-sensitive HS sensor based on sunflower-like In-doped ZnO with enriched oxygen vacancies.

Metal oxide sensors face the challenge of high response and fast recovery at low operating temperatures for the detection of toxic and flammable hydrogen sulfide (HS) gases. Herein, novel In-doped ZnO with a sunflower-like structure and tunable surface properties was rationally synthesized. The substitutional In atom in the ZnO crystal can dramatically enhance the concentration of oxygen vacancies (O), the In-ZnO sites are responsible for fast recovery, and the formation of sub-stable sulfide intermediates gives rise to the high response towards HS.

Treatment dependent sodium-rich Prussian blue as a cathode material for sodium-ion batteries.

In the preparation of Prussian blue analogs (PBAs), Na loss and Fe oxidation take place when washing with water. Sodium-rich PBAs were prepared with sodium ascorbate aqueous solution as the washing solution, which can suppress the Na loss and Fe oxidation. As the cathode of sodium-ion batteries, it exhibited excellent electrochemical performance.

, a Potential Pathogen in Freshwater-Cultured Hybrid Sturgeon.

In July 2021, a disease with a high mortality rate broke out in freshwater cultured hybrid sturgeon in Zhengzhou, Henan Province. A dominant strain, H-701, was isolated from diseased fish; physiological changes in diseased fish were investigated and molecular identification, biochemical characterization, and pathogenicity and drug sensitivity tests of H-701 were performed. The 16S rRNA gene sequence of H-701 was 99.

Electron cloud migration effect-induced lithiophobicity/lithiophilicity transformation for dendrite-free lithium metal anodes.

Enabling stable lithium metal anodes is significant for developing electrochemical energy storage systems with higher energy density. However, safety hazards, infinite volume expansion, and low coulombic efficiency (CE) of lithium metal anodes always hinder their practical application. Herein, a nano-thickness lithiophilic Cu-Ni bimetallic coating was synthesized to prepare dendrite-free lithium metal anodes.

Advances in Doped ZnO Nanostructures for Gas Sensor.

Gas sensors based on metal oxides semiconductor (MOS) have attracted extensive attention from both academic and industry. ZnO, as a typical MOS, exhibits potential applications in toxic gas detection, owning to its wide band gap, n-type transport characteristic and excellent electrical performance. Meanwhile, doping is an effective way to improve the sensing performance of ZnO materials.

Ultrathin agaric-like ZnO with Pd dopant for aniline sensor and DFT investigation.

Aniline detection is of great importance in many industries, but most of the aniline sensors suffers from tedious and time consuming process. Herein, we present an efficient aniline sensor based on Pd decorated ZnO nanomaterials. Ultrathin ZnO nanosheets were synthesized by a facile one-step hydrothermal method.

The Suitability of Different Subtypes and Dimensions of Obsessive-Compulsive Disorder for Treatment with Anterior Capsulotomy: A Long-Term Follow-Up Study.

Objective: Anterior capsulotomy (AC) is sometimes used as a life-saving treatment for patients with treatment-refractory obsessive-compulsive disorder (Tr-OCD). Most of the previous studies have assessed only total symptoms and have concluded that AC is a safe and effective procedure. Few of these studies have focused on meticulously investigating the variety of results obtained from patients with different subtypes of OCD.

Double-platelet Pd@ZnO microcrystals for NO chemical sensors: their facile synthesis and DFT investigation.

Double-platelet, single-platelet and spherical ZnO microcrystals were fabricated via a facile and controllable hydrothermal method. The morphology of the ZnO microcrystals and the exposure ratio of the (001) crystal surface were regulated by adjusting the pH of the solution. The ZnO microcrystals were modified with Pd nanoparticle loading by simple calcining, and the interaction of Pd nanoparticles (NPs) on the ZnO crystal surface increased its oxygen vacancy content.

Pineal Region Gliomas: A Single-Center Experience with 25 Cases.

Background: Pineal region glioma is a rare systematically reported tumor in the literatures, and little is known about its behavior, development, and best treatment strategies because of its complex anatomical relationship and rarity.

Objective: We reviewed the outcomes of patients with pineal region gliomas in West China hospital in the past 5 years and searched the literature to add more information. As a result, key factors related to prognosis are identified.

Quantifying blood-brain-barrier leakage using a combination of evans blue and high molecular weight FITC-Dextran.

Background: Evans blue (EB) is the most widely used tracer to assess BBB leakage. However, a well-established method to obtain visualized and quantitative results of EB extravasation is presently unavailable.

New Method: We reported a novel method to quantify BBB leakage by combining EB and high molecular weight FITC-Dextran (2000 kDa).