Publications by authors named "FeiHang Wang"
Objectives: To compare the diagnostic accuracy of 3D contrast-enhanced ultrasound (CEUS)/MRI-CEUS fusion imaging with 2D-CEUS in assessing the response of hepatocellular carcinoma (HCC) to locoregional therapies in a multicenter prospective study.
Materials And Methods: A consecutive series of patients with HCC scheduled for locoregional treatment were enrolled between April 2021 and March 2023. Patients were randomly divided into 3D-CEUS/MRI-CEUS fusion imaging group (3D/fusion group) or 2D-CEUS group (2D group).
Background: Thyroid nodule (TN) patients in China are subject to overdiagnosis and overtreatment. The implementation of existing technologies such as thyroid ultrasonography has indeed contributed to the improved diagnostic accuracy of TNs. However, a significant issue persists, where many patients undergo unnecessary biopsies, and patients with malignant thyroid nodules (MTNs) are advised to undergo surgery therapy.
View Article and Find Full Text PDFMeIS: DNA Methylation-Based Immune Response Signatures for Thyroid Nodule Diagnostics.
J Clin Endocrinol Metab
August 2024
Context: Accurately distinguishing between benign thyroid nodules (BTNs) and papillary thyroid cancers (PTCs) with current conventional methods poses a significant challenge.
Objective: We identify DNA methylation markers of immune response-related genes for distinguishing BTNs and PTCs.
Methods: In this study, we analyzed a public reduced representative bisulfite sequencing dataset and revealed distinct methylation patterns associated with immune signals in PTCs and BTNs.
Background: Pulmonary oligometastases are common in hepatocellular carcinoma (HCC), however, the existing therapeutic options have several limitations. This study aimed to assess the safety and efficacy of microwave ablation (MWA) in the treatment of HCC-originating pulmonary oligometastases.
Methods: A total of 83 patients, comprising 73 males and 10 females with a median age of 57 years, who had pulmonary oligometastases from HCC, underwent MWA treatment at four different medical institutions.
Article Synopsis
- - Hepatic reactive lymphoid hyperplasia (RLH) is a rare, benign condition that can mimic more serious liver diseases like cancer, posing challenges for diagnosis, particularly with imaging techniques and biopsies.
- - In a case involving a 69-year-old woman, imaging suggested metastatic liver cancer, leading to surgery, but the final diagnosis revealed RLH after histopathological examination.
- - The study emphasizes the importance of assessing specific imaging features, such as "wash-in and wash-out" patterns and diffusion on MRI, to better identify RLH in older women with isolated liver nodules and no cancer risk factors.
Background: Intrahepatic cholangiocarcinoma (iCCA) is an aggressive primary liver cancer with dismal outcome, high Ki-67 expression is associated with active progression and poor prognosis of iCCA, the application of MRE in the prediction of iCCA Ki-67 expression has not yet been investigated until now. We aimed to evaluate the value of magnetic resonance elastography (MRE) in assessing Ki-67 expression for iCCA.
Results: In the whole cohort, 97 patients (57 high Ki-67 and 40 low Ki-67; 58 males, 39 females; mean age, 58.
Article Synopsis
- The study aimed to compare the safety and effectiveness of intraluminal brachytherapy using iodine-125 (I) seeds in patients with obstructive jaundice caused by tumor thrombus, focusing on those who had stents placed versus those who did not.
- A total of 42 patients were analyzed; group A received both I seed strands and stents while group B received only I seed strands.
- Results showed that while there was no significant difference in overall survival or jaundice-free survival between the two groups, the study concluded that iodine-125 brachytherapy is both effective and safe for this condition.
To investigate associations between MRI features and high-frequency mutations of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). This study included 58 HCC patients who underwent contrast-enhanced MRI prior to surgical resection and genome sequencing. MRI features and mutation information were evaluated.
View Article and Find Full Text PDFBackground: To evaluate the prognostic value of the pre-treatment aspartate transaminase (AST)/alanine transaminase (ALT) ratio in hepatocellular carcinoma (HCC) patients receiving radiofrequency ablation (RFA)/microwave ablation (MWA) combined with simultaneous TACE.
Methods: The data for 117 patients were retrospectively analyzed in this study. The endpoint of prognosis was overall survival (OS).
Background: Microvascular invasion (MVI) is a well-established poor prognostic factor for hepatocellular carcinoma (HCC). Preoperative prediction of MVI is important for both therapeutic and prognostic purposes, but noninvasive methods are lacking.
Purpose: To develop an MR elastography (MRE)-based nomogram for the preoperative prediction of MVI in HCC.
Objective: This retrospective study compares the clinical results of cone beam CT (CBCT)-guided thermal ablation with those of helical tomotherapy in hepatocellular carcinoma (HCC) patients with pulmonary metastases.
Methods: A total of 110 patients undergoing thermal ablation or helical tomotherapy for pulmonary metastases from April 2014 to December 2020 were included in the study. The endpoints were local tumor progression-free survival (LTPFS), overall survival (OS), and complications.
Purpose: To investigate the clinical outcomes of microwave ablation (MWA) combined with lipiodol-microsphere mixed transarterial chemoembolization (mTACE) or conventional TACE (cTACE) for patients with colorectal liver metastases (CRLM).
Materials And Methods: This retrospective study evaluated the medical records of patients with CRLM who underwent MWA combined with mTACE or cTACE from January 2018 to September 2021. The objective response rate (ORR), disease control rate (DCR), progression-free survival (PFS) and overall survival (OS) were evaluated during the follow-up.
Objective: This study aimed to investigate the application value of contrast-enhanced ultrasound (CEUS) before and after minimally invasive ablation procedures for benign thyroid nodule(s) (BTN).
Methods: This prospective study included patients with BTNs scheduled to undergo ultrasound-guided minimally invasive ablation treatment. CEUS was performed before and after ablation (at 1 day, and 1, 6, and 12 months after ablation).