Unraveling the genetic basis of grain number-related traits in a wheat-Agropyron cristatum introgressed line through high-resolution linkage mapping.

Background: Grain number per spike (GNS) is a pivotal determinant of grain yield in wheat. Pubing 3228 (PB3228), a wheat-Agropyron cristatum germplasm, exhibits a notably higher GNS.

Results: In this study, we developed a recombinant inbred line (RIL) population derived from PB3228/Gao8901 (PG-RIL) and constructed a high-density genetic map comprising 101,136 loci, spanning 4357.

Accuracy of different registration areas using active and passive dynamic navigation systems in dental implant surgery: An in vitro study.

Objectives: To gauge the relative accuracy of the use of passive and active dynamic navigation systems when placing dental implants, and to determine how registration areas affect the performance of these systems.

Materials And Methods: Eighty implants were assigned to be placed into 40 total resin mandible models missing either the left or right first molars using either passive or active dynamic navigation system approaches. U-shaped tube registration devices were fixed in the edentulous site for 20 models each on the left or right side.

Analysis of the accuracy of a dynamic navigation system when performing dental implant surgery with transcrestal sinus floor elevation: A pilot study.

Background/purpose: The success of transcrestal sinus floor elevation (TSFE) is primarily reliant upon the experience of the surgeon owing to the limited operative visibility. To evaluate the accuracy associated with the use of a dynamic navigation system when conducting posterior maxilla implant surgery with TSFE.

Materials And Methods: Twenty-eight implants were placed in 28 patients requiring implantation in the posterior maxilla via a TSFE approach.

Relationships between physical activity, fundamental motor skills, and body mass index in preschool children.

Purpose: To investigate whether there is a potential relationship between physical activity (PA), fundamental motor skills (FMS), and Body Mass Index (BMI) in preschool children and to further explore the differences in PA and FMS between normal-weight and overweight/obese preschool children.

Method: Participants were 366 preschool children aged 3 to 6 years; 358 completed all tests (194 boys and 164 girls). PA, FMS, body weight, and height were measured by triaxial accelerometer, the Test of Gross Motor Development, Second Edition (TGMD-2), and anthropometry measurement, respectively.

[Effects of TUG1 on hepatic fibrosis and its mechanism].

To investigate the effects and mechanisms of taurine up-regulated gene 1 (TUG1) in hepatic fibrosis. According to the literature, the classic hepatic fibrosis model of rats induced by 1%DMN(1ml/kg/d) was established. The rats with hepatic fibrosis and activated hepatic stellate cells (HSC) were divided into model control group, negative control group (transfected with siRNA negative control), siRNA interference group (transfected with TUG1).

Dysregulated NF-κB signal promotes the hub gene PCLAF expression to facilitate nasopharyngeal carcinoma proliferation and metastasis.

Background: Nasopharyngeal carcinoma (NPC) is common in Southern China. The molecular mechanism underlying NPC genesis and progression has been comprehensively investigated, but the key gene (s) or pathway (s) pertaining to NPC are unidentified.

Methods: We explored some key genes and pathways involved in NPC through using meta-analysis of deposited expression of microarray data of NPC.

Three Novel ACE Inhibitory Peptides Isolated From Seeds: Purification, Inhibitory Kinetic and Mechanism.

Alcalase, dispase, trypsin, and flavourzyme were used to hydrolyze the extracted seeds protein isolate (GPI). The protein hydrolyzates (GPHs) with the maximum degree of hydrolysis (DH) and ACE inhibitory activity were selected, and ultra-filtered to obtain components with different molecular weights (MW) (<1 kDa, 1-3, 3-5, and 5-10 kDa). The components with MW of <1 kDa showed better ACE inhibition (IC:0.

Effect of superfine grinding on properties of Thunb leaves powder.

Thunb, have been widely used in various traditional medicines and food products. The narrow and uniform particle size distribution in Thunb leaves (VBTL) can be achieved through a new emerging type of foodstuff processing and superfine grinding. The VBTL powders were subjected to four particle sizes as followed: 300-125, 125-75, 75-40, and <40 μm.

Hypermethylation of AKT2 gene is associated with neural-tube defects in fetus.

Introduction: Neural-tube defects (NTDs) are common birth defects of complex etiology. Although many studies have confirmed a genetic component, the exact mechanism between DNA methylation and NTDs remains unclear.

Methods: In this work, we investigated the alteration of methylation from placental tissues obtained from 152 normal infants or with NTDs in 130 children with neural-tube defects.

Association between Long Interspersed Nuclear Element-1 Methylation and Relative Telomere Length in Wilms Tumor.

Background: DNA hypomethylation of long interspersed nuclear elements-1 (LINEs-1) occurs during carcinogenesis, whereas information addressing LINE-1 methylation in Wilms tumor (WT) is limited. The main purpose of our study was to quantify LINE-1 methylation levels and evaluate their relationship with relative telomere length (TL) in WT.

Methods: We investigated LINE-1 methylation and relative TL using bisulfite-polymerase chain reaction (PCR) pyrosequencing and quantitative PCR, respectively, in 20 WT tissues, 10 normal kidney tissues and a WT cell line.

MiR-34b/c rs4938723 Polymorphism Significantly Decreases the Risk of Digestive Tract Cancer: Meta-analysis.

Background: Previous studies investigating the association between miR-34b/c rs4938723 polymorphism and cancer risk showed inconclusive. Here, we performed meta-analysis to investigate the association between miR- 34b/c rs4938723 polymorphism and digestive cancer risk.

Materials And Methods: Literature database including PubMed, OVID, Chinese National Knowledge Infrastructure (CNKI) were searched for publications concerning the association between the miR-34b/c rs4938723 polymorphism and digestive cancer risk.

[Normal occlusion study: using T-Scan III occlusal analysis system].

Objective: To investigate the normal occlusal force distribution and the characteristics of the occlusion time at different occlusion position using T-Scan III occlusal analysis system.

Methods: Fifty-three volunteers with normal occlusion, including 29 males and 24 females, were included in this study. The average age was (25.