Publications by authors named "Fei-Zhou Zhu"
Chin Med J (Engl)
December 2019
Article Synopsis
- The study investigates the roles of CD4 and CD8 T cells in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), revealing that both types are involved in the disease process.
- Using female mice, researchers isolated and analyzed T cells to see how they respond to the myelin oligodendrocyte glycoprotein (MOG) peptide, focusing on their proliferation and cytokine secretion.
- The findings show that while CD8 T cells respond differently than CD4 T cells, particularly in cytokine production, they can still contribute to the clinical manifestations of EAE similarly to CD4 T cells.
