Publications by authors named "Fei-Ya Luo"
In the present study, the oral bioavailability of cadmium (Cd) in earthworms and leeches was investigated through in vitro physiologically based extraction test (PBET) digestion/Caco2 and MDKC cell models. We are the first to create an innovative assessment strategy which has capacity to offer a more precise evaluation of Cd-associated health risks in traditional animal medicines (TAMs), by combinational usage of bioavailable Cd levels, the duration and frequency of the exposure to TAMs obtained by questionnaire data, as well as safety factor of TAMs. Our data showed that the percentage of bioavailability for Caco-2 cells in earthworms and leeches ranged from 3.
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- Few studies have examined the heavy metal accumulation in traditional Chinese medicines (TCMs), specifically investigating lead, cadmium, arsenic, mercury, and copper in traditional animal medicines.
- The research introduced a comprehensive health risk assessment approach that evaluates the bioaccessible levels of these heavy metals, calculating metrics like target hazard quotient (THQ), target hazard index (THI), and cancer risk (CR).
- Findings indicated that mercury had the lowest bioaccessibility, and overall, traditional animal medicines appear to pose a minimal health risk to the general community, with cancer risk levels for arsenic and lead remaining below accepted clinical thresholds.