Publications by authors named "Fei-Fei Liang"

Background: The aging of the population has become increasingly obvious in recent years, and the incidence of cerebral infarction has shown an increasing trend annually, with high death and disability rates.

Aim: To analyze the effects of infarct location and volume on cognitive dysfunction in elderly patients with acute insular cerebral infarction.

Methods: Between January 2020 and December 2023, we treated 98 cases of elderly acute insula, patients with cerebral infarction in the cerebral infarction acute phase (3-4 weeks) and for the course of 6 months in Montreal Cognitive Assessment Scale (MoCA) for screening of cognition.

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Article Synopsis
  • - A new method has been created for synthesizing complex allyl cinnamates using palladium (Pd) as a catalyst in a three-part reaction.
  • - The process involves activating carbon-carbon (C-C) bonds followed by a substitution reaction, utilizing a specific hydrolysis product from cyclopropenone.
  • - The study explored the reaction's mechanism, highlighting its ability to produce high stereoselectivity and efficient use of materials (atomic economy).
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Background: Currently, high expression of WD repeat and HMG-box DNA binding protein 1 (WDHD1) has been found in a variety of tumors; but there is no research has been conducted concerning the expression of WDHD1 in laryngeal squamous cell carcinoma (LSCC). Our purpose is to investigate the expression and the latent mechanism of WDHD1 in LSCC.

Methods: Firstly, 9 data sets from the Gene Expression Omnibus (GEO), The Cancer Genome Atlas (TCGA), and ArrayExpress were statistically analyzed to explore the expression of WDHD1 in LSCC; immunohistochemistry was performed in 79 LSCC tissues and 44 non-cancer tissues to further verify the result.

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  • The study examines how half-brain delineation can help predict radiation damage in the temporal lobes of patients with nasopharyngeal carcinoma (NPC) undergoing intensity-modulated radiotherapy (IMRT).
  • A retrospective analysis of 220 NPC cases showed significant differences in radiation doses received by the temporal lobes compared to half-brains, with specific dosimetric parameters demonstrating varying degrees of prediction accuracy for temporal lobe injury (TLI).
  • The findings suggest that using half-brain delineation simplifies the contouring process and provides reliable estimates for TLI risk, making it a practical approach for NPC patient treatment planning.
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Objective: To investigate the effect of Sarcandra glabra in scavenging reactive oxygen species (ROS) produced by γ-ray irradiation in the parotid gland of miniature pigs.

Methods: Forty-five male miniature pigs were randomly divided into control group, radiation group and radiation plus medication group, and each group contained 3 parallel groups (subgroups a, b and c). From 1 week before exposure of the parotid gland region to 15 Gy γ-ray irradiation (which was not administered in the control group), the miniature pigs in radiation plus medication group were given Sarcandra glabra powder, while those in the other groups received an equal amount of saline.

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