Publications by authors named "Fei-Fan Chen"
A case of Gastric cystic polyp mimicking early gastric cancer.
J Gastrointestin Liver Dis
December 2024
In this study, we present a case of a 51-year-old man with a gastric lesion initially suspected to be early gastric cancer but was ultimately diagnosed as a Gastric cystic polyp (GCP). The patient underwent diagnostic endoscopic submucosal dissection (ESD) based on the lesion's appearance and characteristics. Detailed pathological and immunohistochemical analysis confirmed the diagnosis of GCP.
View Article and Find Full Text PDFThe purpose of this study was to comprehensively analyze the genetic diversity of the Pekin duck conserved population with five generations and to evaluate the effectiveness of the current conservation strategy. In total, 277 Pekin duck conserved individuals and 40 Mallards as ancestral controls were collected. Each duck was sequenced at about 10X whole-genome coverage, while over 7.
View Article and Find Full Text PDFBackground: Composite tumors are neoplasms comprising two distinct, yet intermingling, cell populations. This paper reports a rare phenomenon where early gastric signet-ring cell carcinoma (SRCC) and gastric mucosa-associated lymphoid tissue (MALT) lymphoma coexist within the same lesion.
Case Summary: A 40-year-old woman presented to the West China Hospital for examination, which revealed a whitish, shallow, and uneven mucosal lesion in the stomach.
The "real world" treatment mode and clinical efficacy of locally advanced esophageal squamous cell carcinoma (LAESCC) are unclear. Meanwhile, the role of immunotherapy in the clinical practice is also puzzling. We conducted the research to investigate the statue of "real world" LAESCC.
View Article and Find Full Text PDFArticle Synopsis
- Intervertebral disc degeneration (IDD) is a common condition that leads to low back pain, and increasing ECM synthesis while decreasing NPC apoptosis may help restore function in degenerated discs.
- Researchers identified LIM mineralization protein-1 (LMP-1) as a promising target for treatment due to its anti-inflammatory properties and its high expression in the nucleus pulposus (NP) of patients.
- The study found that overexpressing LMP-1 in NPCs enhanced cell proliferation, reduced apoptosis, and increased collagen II and sulfated glycosaminoglycan synthesis, suggesting its potential role in IDD treatment by regulating NF-κB signaling.