Introduction: With an incidence rate as high as 46%-58%, hypoglycemia is a common complication of glycemic management among those suffering from type 2 diabetes mellitus(T2DM). According to preclinical research, hypoglycemia episodes may impair cognition by harming neurons. However, there is still controversy regarding the clinical evidence for the relationship between hypoglycemic events and the likelihood of cognitive impairment.
View Article and Find Full Text PDFThe light absorption and fluorescence characteristics of atmospheric water-soluble organic compounds (WSOC) and humic-like substances (HULIS) during the winter season in Guangzhou were examined using UV-vis spectroscopy and excitation-emission matrix spectroscopy combined with parallel factor analysis (EEM-PARAFAC). The results showed that the SUVA, HIX, and MAE values of HULIS were higher than those of WSOC, suggesting that the former had higher aromaticity, humification, and light-absorption capacity in winter atmospheric PM in Guangzhou. EEM-PARAFAC analysis identified three fluorescence components, including fulvic-like acid (C1), humic-like acid (C2), and protein-like (C3) components.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
March 2017
Objective: For the purpose of an early identification of intervention targets for acute spinal cord injury (ASCI), we investigated the changes in expression levels of microRNA-9 (miR-9) and MCPIP1 in rat ASCI model.
Method: A total of 108 healthy rats were randomly divided into non-ASCI group (n=18) and five ASCI groups, 6h, 12h, 24h, 3 days and 7 days, representing the experimental time points following ASCI (n=18 per group). Hematoxylin and eosin (HE) staining was used to assess the ASCI damage, and quantitative real-time PCR (qRT-PCR) and in situ hybridization (ISH) were employed for the detection of miR-9 and MCPIP1 mRNA expression.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
June 2013
Objective: To understand the effect of comprehensive schistosomiasis control measures with focus on buffalo and sheep removal in Anxiang City, Dongting Lake area.
Methods: The data of buffalo and sheep removal, routine schistosomiasis control measures such as disease detection and treatment, Oncomelania snail survey and control, as well as health education were collected and analyzed in Anxiang County, Hunan Province from 2004 to 2012.
Results: The schistosome infection rates of people, domestic animals and snails decreased from 11.
World J Gastroenterol
August 2009
Aim: To investigate the correlation between the expression levels of interleukin (IL)-6 and proteins in tight junctions (TJs) in the esophageal mucosa of rats modeling different types of reflux esophagitis (RE), and the ability of aluminum phosphate to protect against RE-induced mucosal damage via these proteins.
Methods: Male SPF Wistar rats aged 56 d were divided randomly into acid RE, alkaline RE, mixed RE, and control groups. Various surgical procedures were performed to establish rat models of acid RE.
Zhong Xi Yi Jie He Xue Bao
November 2003