Chromosome-level genome assembly of Monolepta hieroglyphica, two-spotted leaf beetle (Coleoptera: Chrysomelidae).

Monolepta hieroglyphica, in view of its wide-ranging host and highly polyphagous characteristics, has become an important agricultural pest in East and Southeast Asian countries. To better understand its biology and develop control strategies, we present a high-quality chromosome-level genome assembly of M. hieroglyphica, with contig N50 of 18.

Identification and characterization of playing a positive role in the abiotic stress resistance of Chinese chestnut via an integrated strategy.

Chinese chestnut ( Blume) is an important economic forest tree species and mainly cultivated in mountainous areas and wastelands, subjecting it to various abiotic stresses. The protein phosphatase 2C (PP2C) genes contributes largely to stress responses in plants. However, the characteristics and functions of genes in remain unknown.

Ion flux regulating with Au-modified separator to realize a homogenize Zn metal deposition.

Aqueous Zn-ion batteries (AZIBs) have attracted widespread attention owing to the feature of low cost, inherent safety and eco-friendliness. However, the poor reversibility of Zn anode severely hinders the practical applicability of AZIBs. Separator modification is an effective way to functionalize the electrode/electrolyte interface and improve the cycling performance.

[Retracted] Targeting of TLE3 by miR‑3677 in human breast cancer promotes cell proliferation, migration and invasion.

[This retracts the article DOI: 10.3892/ol.2019.

Microencapsulation of Chenpi extract with soy oligopeptides: enhanced retention of flavor compounds and improved bioaccessibility of polyphenolics.

Background: Chenpi extract (CPE) is rich in polyphenols, flavonoids, and volatile flavor compounds, and possesses numerous healthy biological effects. However, the low stability and bioaccessibility of CPE significantly limits its application in food development.

Results: In this study, CPE microcapsules were prepared using soybean oligopeptide (SOP), maltodextrin (MD), soybean protein isolate (SPI), and citrus insoluble dietary fiber (CIDF) as the encapsulants.

Physical activity promotes the development of cognitive ability in adolescents: the chain mediating role based on self-education expectations and learning behaviors.

Cognitive ability plays a crucial role in adolescents' academic performance and subsequent career development. Although previous studies have demonstrated that physical activity, self-education expectations, and learning behaviors positively affect the cognitive development of adolescents, the extent of their influence and their mediating roles require further elucidation. This study is based on tracking survey data from 2,688 adolescents in Chinese households collected in 2018.

Selectively Quantify Toxic Pollutants in Water by Machine Learning Empowered Electrochemical Biosensors.

Electroactive biofilm (EAB) sensors have become pivotal in water quality detection and early ecological risk warnings due to their remarkable sensitivity. However, it is challenging to identify multiple toxicants in complex water bodies concurrently. This research developed an innovative biosensor detection strategy combined with machine learning.

Metasurface-Based Image Classification Using Diffractive Deep Neural Network.

The computer-assisted inverse design of photonic computing, especially by leveraging artificial intelligence algorithms, offers great convenience to accelerate the speed of development and improve calculation accuracy. However, traditional thickness-based modulation methods are hindered by large volume and difficult fabrication process, making it hard to meet the data-driven requirements of flexible light modulation. Here, we propose a diffractive deep neural network (DNN) framework based on a three-layer all-dielectric phased transmitarray as hidden layers, which can perform the classification of handwritten digits.

The Role of in Regulating Internal Browning Involves Flavonoid Biosynthesis and the Endophytic Fungal Community of Pineapple.

Endophytic fungi are commonly used to control plant diseases, overcoming the drawbacks of chemical agents. The internal browning (IB) of postharvest pineapple fruit, a physiological disease, leads to quality losses and limits industrial development. This work investigated the relationship among the effects of (An) on IB controlling, flavonoid metabolism and the endophytic fungal community of pineapple through metabolomics, transcriptomics, microbiomics and microorganism mutagenesis technology.

ITGB4/GNB5 axis promotes M2 macrophage reprogramming in NSCLC metastasis.

Objective: Metastasis of non-small cell lung cancer (NSCLC) is a leading cause of high mortality. In recent years, the role of M2 macrophages in promoting tumor metastasis within the tumor microenvironment has garnered increasing attention. This study aims to investigate the role and potential mechanisms of the ITGB4/GNB5 axis in regulating M2 macrophage reprogramming and influencing NSCLC metastasis.

Electrocatalytic conversion of nitrate to ammonia on the oxygen vacancy engineering of zinc oxide for nitrogen recovery from nitrate-polluted surface water.

Nitrate pollution in surface water poses a significant threat to drinking water safety. The integration of electrocatalytic reduction reaction of nitrate (NORR) to ammonia with ammonia collection processes offers a sustainable approach to nitrogen recovery from nitrate-polluted surface water. However, the low catalytic activity of existing catalysts has resulted in excessive energy consumption for NORR.

Impact of non-invasive ventilation on microbial colonisation patterns in preterm infants: a single-centre study.

Objective: The objective of this study is to assess the relationship between non-invasive ventilation (NIV) and the colonisation of oral and nasal microbiota in preterm infants within the neonatal intensive care unit (NICU).

Design: A prospective cohort study.

Setting: The NICU of Zhejiang University Children's Hospital.

Rapid Hemostasis Tumor In Situ Hydrogel Vaccines for Colorectal Cancer Chemo-Immunotherapy.

Due to the high heterogeneity and the immunosuppressive microenvironment of tumors, most single antigen tumor vaccines often fail to elicit potent antitumor immune responses in clinical trials, resulting in unsatisfactory therapy effects. Hence, personalized tumor vaccines have become a promising modality for cancer immunotherapy. Here, we have developed a tumor in situ hydrogel vaccine (AH/DA-OR) capable of rapid hemostasis for personalized tumor immunotherapy, composed of dopamine-grafted hyaluronic acid (HA/DA) combined with sodium alginate (ALG), with coloaded oxaliplatin (OXA) and resiquimod (R848).

Effect of Dietary Supplementation of Glycerol Monolaurate on Growth Performance, Digestive Enzymes, Serum Immune and Antioxidant Parameters, and Intestinal Morphology in Black Sea Bream.

An eight-week feeding trial was conducted to examine the impact of dietary supplementation with glycerol monolaurate (GML) on juvenile black sea bream. A basal diet was formulated containing 24% fish meal, while five additional diets were prepared, each supplemented with varying levels of GML: GML1 (0.01%), GML2 (0.

Hysteresis response of carbon release and nitrate reduction in polymer denitrification systems.

Polymer denitrification has received much attention in the field of advanced wastewater treatment. It can release carbon source stably during long-term operation, which can be used as electron donor for denitrification. However, the response of the polymer denitrification system to the transient changes of nitrate is not sufficiently disclosed yet.

A proposed biomarker for human citric acid ester (CAE) exposure, and the potential disturbance on human lipid metabolism.

Citric acid esters (CAEs), as one class of important alternative plasticizers, have been proven to be ubiquitous in the environments, leading to an increasing concern regarding their potential health risk to humans. However, information regarding the biomarkers for human CAE biomonitoring is currently unknown. In the present study, we investigated the metabolism characteristics of CAEs by use of in vitro rat liver microsomes (RLMs) and in vivo mice.

[Application of chromatographic retention time correction in untargeted screening].

Objective: Chromatographic retention time correction is one of the important steps to effectively improve the accuracy of identification. This article proposed a strategy for untargeted screening of biological samples based on retention time correction.

Methods: A pre-treatment method for biological samples was established.

Employ machine learning to identify NAD+ metabolism-related diagnostic markers for ischemic stroke and develop a diagnostic model.

Ischemic stroke (IS) is a severe condition regulated by complex molecular alterations. This study aimed to identify potential nicotinamide adenine dinucleotide (NAD+) metabolism-associated diagnostic markers of IS and explore their associations with immune dynamics. Weighted Gene Co-expression Network Analysis and single-sample gene set enrichment analysis (ssGSEA) were employed to identify key gene modules on the GEO dataset (GSE16561).

Calcium silicate hydrate complex konjac glucomannan-based hydrogel selectively adsorbed phosphate in low alkalinity solution.

The selective recovery of phosphate from wastewater can manage nutrients and realize the recycling of phosphorus resources. In this study, a novel konjac glucomannan/pectin/calcium silicate composite hydrogel (KP-CSH) was developed for efficient recovery of phosphate in aqueous solution. The amount of alkali released after the reaction of KP-CSH in a neutral solution was small (the pH of the solution after the reaction was < 9).

[Risk factors for initial non-invasive ventilation failure in very low birth weight infants with gestational age <32 weeks: a multicenter retrospective study].

Objectives: To investigate the risk factors and adverse prognosis associated with initial non-invasive ventilation (NIV) failure in very low birth weight infants (VLBWI) with gestational age <32 weeks.

Methods: A retrospective collection of clinical data from preterm infants admitted to the neonatal intensive care unit (NICU) in 28 tertiary hospitals in Jiangsu Province from January 2019 to December 2021 was conducted. Based on the outcomes of initial NIV, the infants were divided into a successful group and a failure group to analyze the risk factors for NIV failure and adverse prognosis.

Upregulation of NFE2L1 reduces ROS levels and α-synuclein aggregation caused by GBA1 knockdown.

Biallelic mutations in the GBA1 gene result in Gaucher disease (GD), and both patients with GD and carriers of a single GBA1 mutation have an increased susceptibility to Parkinson's disease (PD), but the underlying mechanisms of this association are not yet clear. In previous studies, we established Gba1 F213I point mutation mice and found that homozygous Gba1 F213I mutant mice died shortly after birth, while heterozygous mice could survive normally. In this study, we investigated the transcriptomic changes in the brain tissue of Gba1 F213I heterozygous mice, identifying 138 differentially expressed genes.

Comprehensive analysis of the mitogenome reveals abundant tRNA genes and -spliced introns in Lycopodiaceae species.

Lycophytes and ferns represent one of the earliest-diverging lineages of vascular plants, with the Lycopodiaceae family constituting the basal clade among lycophytes. In this research, we successfully assembled and annotated the complete Thunb. (.