Kerr effect in multilayer dielectric coatings.

We report the utilization of the optical Kerr effect in multilayer dielectric coatings, previously discussed only theoretically. We present the design and realization of multilayer dielectric optical structures with layer-specific Kerr nonlinearities, which permit tailoring of the intensity-dependent effects. The modulation depth in reflectance reaches up to 6% for the demonstrated examples of dielectric nonlinear multilayer coatings.

PROGNOSTIC CRITERIA OF VARIOUS CURRENTS OF CROHN'S DISEASE IN CHILDREN.

Objective: To identify clinical, laboratory and morphological prognostic criteria at different during Crohn's disease in children.

Materials And Methods: in 48 patients with primary BC in age from 1 year to 18 years retrospectively evaluated the clinical and medical history, laboratory parameters, used complex morphological study of the intestinal mucosa.

Results: prediction of complicated Crohns diseaseis important to the high humoral activity, small bowel localization process with the identifcation of ulcers, fractures, the presence of such cell populations in the mucosa of the colon as inactive macrophages and young tbroblasts, muscle infrtration of neutrophilic granulocytes plate.

Highly-dispersive mirrors reach new levels of dispersion.

A highly-dispersive mirror with the unprecedented group delay dispersion of -10000 fs in the wavelength range of 1025-1035 nm is reported. Reproducible production of a coating with such a high dispersion was possible due to the recently developed robust synthesis technique. Successful employment of the new highly-dispersive mirror in an oscillator is demonstrated.

High-power multi-megahertz source of waveform-stabilized few-cycle light.

Waveform-stabilized laser pulses have revolutionized the exploration of the electronic structure and dynamics of matter by serving as the technological basis for frequency-comb and attosecond spectroscopy. Their primary sources, mode-locked titanium-doped sapphire lasers and erbium/ytterbium-doped fibre lasers, deliver pulses with several nanojoules energy, which is insufficient for many important applications. Here we present the waveform-stabilized light source that is scalable to microjoule energy levels at the full (megahertz) repetition rate of the laser oscillator.

260-megahertz, megawatt-level thin-disk oscillator.

A Kerr-lens mode-locked (KLM) Yb:YAG thin-disk oscillator delivering 215-fs pulses with 75-W average power and 1.4-MW peak power at a repetition rate of 260 MHz is presented. Self-starting KLM is demonstrated at an output power of 68 W.

Energy scaling of Kerr-lens mode-locked thin-disk oscillators.

Geometric scaling of a Kerr-lens mode-locked Yb:YAG thin-disk oscillator yields femtosecond pulses with an average output power of 270 W. The scaled system delivers femtosecond (210-330 fs) pulses with a peak power of 38 MW. These values of average and peak power surpass the performance of any previously reported femtosecond laser oscillator operated in atmospheric air.

S-nitrosothiols, nitric oxide and proinflammatory cytokines in children with inflammatory bowel disease.

Background: The aim of the study was to investigate the levels of S-nitrosothiols (RSNO) in blood serum of children with inflammatory bowel disease (IBD), nonspecific ulcerative colitis (NUC) and Crohn's disease (CD), and correlate the obtained data with the number of total nitric oxide metabolites (NOx) and proinflammatory cytokines (PC).

Methods: RSNO and NOx were determined by the Griess method and PC by ELISA. We examined 174 children of both genders aged from 6 to 17 years (mean age - 14 years) including 112 children suffering from IBD and 62 children from the control group.

[Use of mathematical models infrared spectroscopy serum in the differential diagnosis of ulcerative colitis and Crohn's disease in children].

Unlabelled: RELEVANCE OF RESEARCH: Inflammatory bowel diseases are among the most severe pathologies in pediatric gastroenterology, often lead to disability. Despite the similarity of the clinic, pathogenetic mechanisms, the question of the differential diagnosis of ulcerative colitis and Crohn's disease is relevant in view of their different prognosis and treatment strategy. In recent years, in medical uses infrared spectroscopy of blood serum for the differential diagnosis of various inflammatory diseases, benign and malignant tumors.

[Forward-morphological criteria of ulcerative colitis relapse and continuous flow in children].

Unlabelled: Inflammatory bowel disease is one of the most difficult groups of pathologies in pediatric gastroenterology, due to the steady growth of their prevalence, offset debut at an earlier age, the increase in the incidence of severe complicated forms. Established clinical, genetic, serologic criteria for progression of ulcerative colitis are contradictory, and some--the reach of most medical institutions.

Purpose: to evaluate the prognostic significance of morphological features of ulcerative colitis relapse and continuous flow.

[The organization of comprehensive rehabilitation of the children presenting with inflammatory intestinal diseases and celiacia under the conditions of a health resort].

In this study we report the experience with the provision of rehabilitative services for the children presenting with long-standing chronic diseases of the digestive organs (ulcerative colitis, Crohn's disease, celiac disease) based at a regional health resort. The possibility of comprehensive rehabilitation was substantiated with the contribution by non-medical specialists including a psychologist, social worker, and educator. A number of organizational problems related to rehabilitation logistics and scientific support have been successfully solved.

Correcting biases in psychiatric diagnostic practice in Northwest Russia: comparing the impact of a general educational program and a specific diagnostic training program.

Background: A general education in psychiatry does not necessary lead to good diagnostic skills. Specific training programs in diagnostic coding are established to facilitate implementation of ICD-10 coding practices. However, studies comparing the impact of these two different educational approaches on diagnostic skills are lacking.