Complement Component C3 Variant (R102G) and the Risk of Neovascular Age-Related Macular Degeneration in a Tunisian Population.

To explore the association between the polymorphism (S/F) p.R102G in the C3 gene and age-related macular degeneration (AMD) in a Tunisian population. The molecular study was performed by polymerase chain reaction using sequence-specific primers (PCR-SSP) in 207 control subjects free of any eye disease (fundus normal) and 145 patients with exudative AMD.

Identifying mutations in Tunisian families with retinal dystrophy.

Retinal dystrophies (RD) are a rare genetic disorder with high genetic heterogeneity. This study aimed at identifying disease-causing variants in fifteen consanguineous Tunisian families. Full ophthalmic examination was performed.

Spectral Domain optical coherence tomography findings in patients with retinitis pigmentosa.

Background Maculopathy is a common complication of retinitis pigmentosa (RP), and compromise the visual acuity of RP patients even in the less advanced stages. Aim To report the morphological macular findings detected by spectral domain optical coherence tomography (SD-OCT) and to determine their prevalence in patients with retinitis pigmentosa (RP). Methods  SD-OCT scans from 100 patients (196 eyes) affected by RP were reviewed.

Epidemiologic study of myopia in a population of schoolchildren in Tunisia.

Background: Uncorrected refractive error has recently been identified as the leading cause of visual impairment in children worldwide. The prevalence of myopia is increasing. Determination of the epidemiology of myopia is important to develop screening strategy.

Characteristics of Astigmatism in a Population of Tunisian School-Children.

Purpose: To evaluate the characteristics of astigmatism in a cross-sectional study of schoolchildren in Tunisia.

Materials And Methods: A random cluster design was used to recruit children from primary schools across urban and rural settings in Tunisia, from 2008 to 2010. A total of 6192 students aged 6-14-years old were enrolled.

Current and emerging treatment options for myopic choroidal neovascularization.

Choroidal neovascularization (CNV) is the main cause of visual impairment in highly myopic patients younger than 50 years of age. There are different treatments for myopic CNV (mCNV), with 5- to 10-year outcomes currently. Chorioretinal atrophy is still the most important determinant factor for visual outcome.

[Epidemiologic study of hyperopia in schoolchildren in Tunisia].

Aim: To study the epidemiological profile and the degree of severity of hyperopia in Tunisia primary school and to assess its effect on school performance.

Methods: A cross-sectional, descriptive survey was conducted among 6-14 aged Tunisian children attending primary urban and rural schools. A total of 6192 children were selected using stratified random cluster sampling.

Vascular endothelial growth factor genetic polymorphisms and susceptibility to age-related macular degeneration in Tunisian population.

Purpose: Three VEGF SNPs (-2578) C/A, (+405) G/C and (+936) C/T were investigated in Tunisian exudative AMD patients in order to determine their association with the disease susceptibility and their influence to intravitreal bevacizumab therapy response.

Methods: 145 AMD patients and 207 age-matched controls were included. 68 patients were treated with intravitreal bevacizumab.

Choroidal thickness measurement in highly myopic eyes using SD-OCT.

Background And Objective: To measure macular choroidal thickness (CT) using spectral-domain optical coherence tomography (OCT) and to investigate the correlation between CT and age, degree of myopia, and history of macular choroidal neovascularization (CNV).

Patients And Methods: A cross-sectional study included 187 highly myopic eyes of 187 patients examined between January and December 2010. The choroid was imaged with spectral-domain OCT by changing the reference position from the vitreous to the choroid.

Bevacizumab injection in patients with age-related macular degeneration associated with poor initial visual acuity.

Purpose. To evaluate functional and anatomic effects of intravitreal bevacizumab in patients with neovascular AMD and initial low visual acuity. Methods.

Intravitreal bevacizumab versus photodynamic therapy for myopic choroidal neovascularization in a North-African population.

Purpose: To compare the 1-year functional and anatomical outcomes of intravitreal bevacizumab (IVB) and photodynamic therapy (PDT) in patients with myopic choroidal neovascularization (CNV).

Methods: Review of retrospectively collected data of 80 eyes in 80 patients with myopic CNV treated with standard PDT (n = 40) or IVB (1.25 mg/ 0.

Intravitreal bevacizumab for the treatment of choroidal neovascularization secondary to angioid streaks: one year of follow-up.

Purpose: To evaluate the efficacy and safety of intravitreal bevacizumab at one year follow-up, for the treatment of choroidal neovascularization (CNV) associated with angioid streaks.

Methods: A retrospective case series of eighteen eyes of 17 patients with CNV secondary to angioid streaks treated with intravitreal bevacizumab between October 2006 and May 2008. Ophthalmic evaluation including best corrected visual acuity (BCVA), slit lamp biomicroscopic examination, optical coherence tomography (OCT) and fluorescein angiography, was performed before and after treatment.

Optical Coherence Tomographic Findings in Berlin's Edema.

Purpose: To describe optical coherence tomography (OCT) findings in a patient with Berlin's edema following blunt ocular trauma.

Case Report: A 26-year-old man presented with acute loss of vision in his left eye following blunt trauma. He underwent a complete ophthalmologic examination and OCT.