[The use of cyclophosphane in the immunodepressive therapy of severe aplastic anemia].

Low course doses of cyclophosphamide (1.9 +/- 0.2 g) were given to postsplenectomy patients with grave aplastic anemia (GAA).

[The role of splenectomy in treating severe aplastic anemia].

Efficacy of splenectomy at initial stage of multimodality treatment of severe aplastic anemia was assessed in 25 patients aged 15-42. None of the patients achieved remission though there was a relief of hemorrhagic syndrome, diminished requirement in transfusion of donor platelets, a persistent rise in the counts of reticulocytes, leukocytes, absolute number of granulocytes in peripheral blood on postoperative days 14-21 and 60. All the patients were subsequently treated with immunodepressants.

[Diagnostic potentials of a precordial mapping method in patients with acute and chronic forms of ischemic heart disease].

Diagnostic potentialities of modified 27 and 30 precordial ECG-leads were defined for rapid assessment of the coronary blood flow in patients with acute myocardial infarction (AMI) and chronic coronary heart disease during an acute pharmacological test. ECG criterita of limiting AMI size and ECG criteria of the ischemic reaction during the pharmacological xantinol nicotinate test were defined. It was proved that the use of multiple ECG leads raised the sensitivity of the ECG method in the diagnosis of AMI by 13.