Clinical significance of type IV vascularization of laryngeal lesions according to the Ni classification.

Background: Scattered, small, dot-like intraepithelial papillary capillary loops (IPCLs) represent type IV epithelial vascularization according to "Ni classification" and are considered to be nonmalignant. According to the European Laryngological Society classification, these loops are malignant vascular changes. This contradiction has high clinical importance; therefore, clarification of the clinical significance of type IV vascularization according to the Ni classification is needed.

Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells.

Intracellular vesicle transport is essential for cellular homeostasis and is partially mediated by SNARE proteins. Endosomal trafficking to the plasma membrane ensures cytokine secretion in dendritic cells (DCs) and the initiation of immune responses. Despite its critical importance, the specific molecular components that regulate DC cytokine secretion are poorly characterised.

Seed priming with endophytic Bacillus subtilis strain-specifically improves growth of Phaseolus vulgaris plants under normal and salinity conditions and exerts anti-stress effect through induced lignin deposition in roots and decreased oxidative and osmotic damages.

Bacillus subtilis is one of the non-pathogenic beneficial bacteria that promote plant growth and stress tolerance. In the present study, we revealed that seed priming with endophytic B. subtilis (strains 10-4, 26D) improved Phaseolus vulgaris L.

Chondrosarcoma of the Thyroid Cartilage Successfully Treated With Partial Resection of the Thyroid Cartilage.

Chondrosarcoma of the thyroid cartilage is a sporadic disease with nonspecific clinical presentation. Smooth swelling of the supraglottic area should arouse suspicion of possible pathology. In addition to laryngoceles, which usually do not have a significant impact, otolaryngologists should consider chondrosarcoma of the thyroid cartilage and indicate computed tomography (CT).

Economic aspects of multiple myeloma: real costs associated with disease in the Slovak Republic.

Health care costs are continuously increasing. Multiple myeloma represents approximately 1% of all malignancies and the 5-year prevalence is 230,000 patients on average. In addition, there is an annual incidence of 3.

Seed Priming with Endophytic Modulates Physiological Responses of Two Different L. Cultivars under Drought Stress.

The protective effects against drought stress of the endophytic bacterium 10-4 were measured by studying the priming response in two wheat ( L.)-Ekada70 (E70) and Salavat Yulaev (SY)-lines, tolerant and susceptible to drought, respectively. 10-4 improved germination and growth parameters under normal conditions in both cultivars with the most pronounced effect observed in cv.

24-epibrassinolide-induced growth promotion of wheat seedlings is associated with changes in the proteome and tyrosine phosphoproteome.

Brassinosteroids (BRs) represent a unique class of steroidal plant hormones that display pronounced growth-promoting activity at very low concentrations. Although many efforts have been made to characterize the molecular basis of BR action, little is known about the mechanisms behind the growth-promoting effect of BRs at protein level. Proteomic analysis of response to the steroid plant hormone 24-epibrassinolide (EBR) in wheat seedling shoots (Triticum aestivum L.

Methyl jasmonate alleviates water stress-induced damages by promoting dehydrins accumulation in wheat plants.

The investigation of dehydrins participation in MeJA-induced protection of wheat plants (Triticum aestivum L.) from drought stress was performed. The dehydration was designed by the presence of mannitol in increasing concentration (3, 4, and 5%) in the growth medium of wheat seedlings.

Middle Ear Adenoma Imitating Late Postoperative Complication.

Here, we present a rare case of middle ear adenoma in a 58-year-old female, which uniquely presented as an unstable open cavity after an endaural atticoantrotomy. Immunohistochemistry confirmed that the tumor produced endocrine and exocrine secretions. The tumor was radically surgically removed.

Pulse dynamics in SESAM-free electrically pumped VECSEL.

Self-starting pulsed operation in an electrically pumped (EP) vertical-external-cavity surface-emitting-laser (VECSEL) without intracavity saturable absorber is demonstrated. A linear hemispherical cavity design, consisting of the EP-VECSEL chip and a 10% output-coupler, is used to obtain picosecond output pulses with energies of 2.8 pJ and pulse widths of 130 ps at a repetition rate of 1.

Wheat germ agglutinin is involved in the protective action of 24-epibrassinolide on the roots of wheat seedlings under drought conditions.

The involvement of wheat germ agglutinin (WGA) in the protective action of 24-epibrassinolide (EBR) against drought stress was studied in the seedling roots of two wheat cultivars differing in drought tolerance. Under dehydration conditions, the contents of ABA and WGA were shown to change significantly in the roots of either drought-tolerant cultivar Omskaya 35 or drought-sensitive cultivar Salavat Yulaev. Meanwhile, accumulation of either ABA or WGA started earlier and was two times greater in plants of drought-tolerant cultivar.

Conical refraction with low-coherence light sources.

We report on conical refraction (CR) with low-coherence light sources, such as light-emitting diodes and decoherentized HeNe laser radiation, and demonstrate different CR patterns. In our experiments, a variation of the pinhole sizes from 25 to 100 µm and the distances to pinhole from 50 to 5 cm reduced spatial coherence of radiation that resulted in the disappearance of the dark Poggendorff's ring in the Lloyd's plane. This is attributed to the interference nature of the Lloyd's distribution and found to be in excellent agreement with the paraxial dual-cone model of conical refraction.

Two-chip power-scalable THz-generating semiconductor disk laser.

We demonstrate a compact two-chip terahertz-emitting vertical-external-cavity surface-emitting laser source, which provides 1 THz output based on intracavity frequency conversion of dual-wavelength emission in a periodically poled lithium niobate crystal. The type-I frequency conversion scheme at room temperature highly benefits from the power-scaling possibilities in a multi-chip cavity with intracavity powers in excess of 500 W.

Conical refraction output from a Nd:YVO laser with an intracavity conerefringent element.

A conical refraction (CR) laser based on an a-cut Nd:YVO laser was demonstrated. By using a KGW crystal as a CR element, a typical laser with a Gaussian intensity output profile was transformed into a laser with conically refracted output. The CR laser delivered 220 mW of output power for 500 mW of pump power.

3D laser nano-printing on fibre paves the way for super-focusing of multimode laser radiation.

Multimode high-power laser diodes suffer from inefficient beam focusing, leading to a focal spot 10-100 times greater than the diffraction limit. This inevitably restricts their wider use in 'direct-diode' applications in materials processing and biomedical photonics. We report here a 'super-focusing' characteristic for laser diodes, where the exploitation of self-interference of modes enables a significant reduction of the focal spot size.

Femtosecond Alexandrite laser passively mode-locked by an InP/InGaP quantum-dot saturable absorber.

An Alexandrite laser passively mode-locked using an InP/InGaP quantum-dot semiconductor saturable absorber mirror (QD-SESAM) was demonstrated. The laser was pumped at 532 nm and generated pulses as short as 380 fs at 775 nm with an average output power of 295 mW. To the best of our knowledge, this is the first report on a passively mode-locked femtosecond Alexandrite laser using a SESAM in general and a QD-SESAM in particular.

Tunable single- and dual-wavelength SHG from diode-pumped PPKTP waveguides.

A compact, all-room-temperature, widely tunable, continuous wave laser source in the green spectral region (502.1-544.2 nm) with a maximum output power of 14.

Involvement of dehydrins in 24-epibrassinolide-induced protection of wheat plants against drought stress.

In this study, we performed a comparative analysis of the physiological and biochemical parameters of wheat cultivars with contrasting drought resistance, drought-resistant Omskaya 35 (O-35) and less drought-resistant Salavat Yulaev (SYu), during 7-day germination under drought stress simulated by 5% mannitol. In addition, we evaluated the effectiveness of pre-sowing seed treatment with 0.4 μM 24-epibrassinolide (EBR) used to increase the resistance of plants of both cultivars to drought stress.

Quantum-dot saturable absorber and Kerr-lens mode-locked Yb:KGW laser with >450 kW of peak power.

The hybrid action of quantum-dot saturable absorber and Kerr-lens mode locking in a diode-pumped Yb:KGW laser was demonstrated. Using a quantum-dot saturable absorber with a 0.7% (0.

Exogenous methyl jasmonate regulates cytokinin content by modulating cytokinin oxidase activity in wheat seedlings under salinity.

The treatment of 4-days-old wheat seedlings with methyl jasmonate (MeJA) in concentration optimal for their growth (0.1 μM) resulted in a rapid transient almost two-fold increase in the level of cytokinins (CKs). MeJA-induced accumulation of CKs was due to inhibition of both cytokinin oxidase (CKX) (cytokinin oxidase/dehydrogenase, EC 1.

574-647 nm wavelength tuning by second-harmonic generation from diode-pumped PPKTP waveguides.

We present a compact, all-room-temperature continuous-wave laser source in the visible spectral region between 574 and 647 nm by frequency doubling of a broadly tunable InAs/GaAs quantum-dot external-cavity diode laser in a periodically poled potassium titanyl phosphate crystal containing three waveguides with different cross-sectional areas (4×4, 3×5, and 2  μm×6  μm). The influence of a waveguide's design on tunability, output power, and mode distribution of second-harmonic generated light, as well as possibilities to increase the conversion efficiency via an optimization of a waveguide's cross-sectional area, was systematically investigated. A maximum output power of 12.

Efficient yellow-green light generation at 561 nm by frequency-doubling of a QD-FBG laser diode in a PPLN waveguide.

A compact high-power yellow-green continuous wave (CW) laser source based on second-harmonic generation (SHG) in a 5% MgO doped periodically poled congruent lithium niobate (PPLN) waveguide crystal pumped by a quantum-dot fiber Bragg grating (QD-FBG) laser diode is demonstrated. A frequency-doubled power of 90.11 mW at the wavelength of 560.

Self-mode-locked quantum-dot vertical-external-cavity surface-emitting laser.

We present the first self-mode-locked optically pumped quantum-dot semiconductor disk laser. Our mode-locked device emits sub-picosecond pulses at a wavelength of 1040 nm and features a record peak power of 460 W at a repetition rate of 1.5 GHz.

Second harmonic generation in a low-loss orientation-patterned GaAs waveguide.

The technology of low-loss orientation-patterned gallium arsenide (OP-GaAs) waveguided crystals was developed and realized by reduction of diffraction scattering on the waveguide pattern. The propagation losses in the OP-GaAs waveguide were estimated to be as low as 2.1 dB/cm, thus demonstrating the efficient second harmonic generation at 1621 nm under an external pumping.

Orange-to-red tunable picosecond pulses by frequency doubling in a diode-pumped PPKTP waveguide.

A compact picosecond all-room-temperature orange-to-red tunable laser source in the spectral region between 600 and 627 nm is demonstrated. The tunable radiation is obtained by second-harmonic generation in a periodically poled potassium titanyl phosphate (PPKTP) multimode waveguide using a tunable quantum-dot external-cavity mode-locked laser. The maximum second-harmonic output peak power of 3.