Publications by authors named "Federico Porporato"
Article Synopsis
- AA-amyloidosis is a common issue in shelter cats, leading to chronic kidney disease, which is the primary cause of death in these animals.* -
- A study analyzed kidney samples from 9 domestic short-hair cats (median age 8 years) post-mortem, revealing all had elevated serum creatinine, proteinuria, and amyloid deposits in both the cortex and medulla.* -
- The findings indicate systemic AA-amyloidosis is prevalent in shelter cats with chronic kidney disease, suggesting these cats can serve as a natural model for studying this condition.*
Article Synopsis
- Systemic AA-amyloidosis is a disease caused by the misfolding of serum amyloid-A protein, leading to its accumulation in various organs; this condition is seen in both humans and animals, including cheetahs and certain domestic cat breeds.
- A study conducted in three shelters found that AA-amyloidosis had high prevalence rates (52.0% to 73.0%) among the shelter cats examined, with many affected cats showing damage in multiple organs.
- The research suggested a potential link between longer shelter stays and more severe amyloidosis, indicating that shelter cats could serve as a natural model for studying this disease and hinting at possible fecal-oral transmission routes through the presence of SAA fragments
Background: Few studies have assessed predictors of outcome in dogs with thyroid tumors undergoing thyroidectomy.
Objective: To estimate the survival and identify prognostic factors in dogs with thyroid tumors treated by thyroidectomy.
Animals: A total of 144 client-owned dogs with thyroid neoplasia that underwent thyroidectomy.
Cutaneous candidiasis is usually related to immunosuppressive diseases and/or therapies as predisposing factors. In humans, chronic mucocutaneous candidiasis (CMC) is observed with thymoma and thymectomy. In this case report we describe the clinical and pathological findings, laboratory analysis, treatment, and follow-up of a thymectomized dog with cutaneous and mucocutaneous generalized candidiasis.
View Article and Find Full Text PDFSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people globally since its first detection in late 2019. Besides humans, cats and, to some extent, dogs were shown to be susceptible to SARS-CoV-2, highlighting the need for surveillance in a One Health context. Seven veterinary clinics from regions with high incidences of coronavirus disease (COVID-19) were recruited during the early pandemic (March to July 2020) for the screening of patients.
View Article and Find Full Text PDFBackground: Feline panleukopenia virus (FPV) is very resistant and highly contagious and infects domestic cats and other felids. FPV is particularly widespread among sheltered cats, and is associated with high morbidity and mortality, causing severe gastroenteritis characterized by anorexia, lethargy, fever, dehydration, hemorrhagic diarrhea, and vomiting. There is currently no data on the ultrasonographic features of cats affected with FPV.
View Article and Find Full Text PDFFeline parvovirus (FPV) causes severe gastroenteritis and leukopenia in cats; the outcome is poor. Information regarding specific treatments is lacking. Class A CpG oligodeoxynucleotides (CpG-A) are short single-stranded DNAs, stimulating type I interferon production.
View Article and Find Full Text PDFOBJECTIVE To determine survival estimates and outcome predictors for shelter cats with feline panleukopenia virus (FPV) infection. DESIGN Retrospective cohort study. ANIMALS 177 shelter cats with FPV infection.
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