Publications by authors named "Federico Pierella"
Article Synopsis
- This study evaluates early bleeding complications after holmium laser enucleation of the prostate (HoLEP) in patients on blood-thinning medications, covering data from January 2020 to February 2023.
- The study categorizes patients into three groups based on their antithrombotic therapy: none, antiplatelet (AP), and anticoagulant (AC), and compares their postoperative outcomes.
- Findings indicate that while HoLEP is generally safe, patients on anticoagulants have a higher risk of minor bleeding complications, and those not on any therapy have shorter hospital stays and catheterization times.
Background: Chronic kidney disease (CKD) is a highly prevalent condition. Urologic disorders are known causes of CKD, but often remain undiagnosed and underestimated also for their insidious onset and slow progression. We aimed to evaluate the prevalence of urological unrecognized diseases in CKD patients by uroflowmetry.
View Article and Find Full Text PDFPurpose: To evaluate the safety and feasibility of ureteroscopy plus elective double-J stent as an outpatient procedure in an unselected population with regard to the treatment for ureteral calculi and to present a multivariate analysis of factors predict hospitalization.
Materials And Methods: Ureteroscopy was performed as an outpatient procedure on 308 consecutive patients with ureteral stones. Contraindication for day case surgery was the only exclusion criteria from the study.
Objectives: The aim of the study was to comparatively evaluate the psychological and functional effect of different primary treatments in patients with prostate cancer.
Methods And Materials: We conducted a single-center prospective non randomized study in a real-life setting using functional and psychological questionnaires in prostate cancer cases submitted to radical prostatectomy, external radiotherapy, or active surveillance. Totally, 220 cases were evaluated at baseline and during the follow-up at 1-, 3-, 6-, and 12-month interval after therapy.
Prostate specific antigen (PSA) test is the most common, clinically validated test for the diagnosis of prostate cancer (PCa). While neoplastic lesions of the prostate may cause aberrant levels of PSA in the blood, the quantitation of free or complexed PSA poorly discriminates cancer patients from those developing benign lesions, often leading to invasive and unnecessary surgical procedures. Microenvironmental acidity increases exosome release by cancer cells.
View Article and Find Full Text PDFProstate is an immune-competent organ normally populated by inflammatory cells. Prostatic inflammation origin can be multi-factorial and there are some emerging evidences on its possible role as a factor involved in prostate cancer (PC) pathogenesis and progression. This review critically analyzes the role of inflammation as a prognostic factor for progression and aggressiveness of PC.
View Article and Find Full Text PDFOur aim was to systematically evaluate the benefits of degarelix as antagonist versus agonists of gonadotropin-releasing hormones (GnRH) for the treatment of advanced prostate cancer (PC). This comparison was performed either in terms of biochemical or oncological or safety profiles. To this end we, carried out a systematic review and meta-analysis of the literature.
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