Multicentre evaluation of glycated haemoglobin (HbA1c) of Roche Diagnostics in Andalusia.

Background: A Spanish multicentre evaluation of the third generation of Roche Diagnostics immunoturbidimetric inhibition method (TINIA) is presented for quantification of haemoglobin A1c (HbA1c) in whole blood.

Methods: The analytical performance of the TINIA test was evaluated and blood sample results were compared with two other widely used analysers, Bio-Rad Variant II and Adams Arkray HA-8160, based on HPLC.

Results: Within- and between-batch imprecision (coefficients of variation (CVs)) for HbA1c levels of 5, 6, 7 and 8% were 0.

Seasonal variability of glycated hemoglobin in a diabetic population from southern Europe.

Aims: To analyze the seasonal variations in A1c levels among a southern European diabetic population.

Methods: We examined all monthly-grouped A1c determinations from diabetic patients during the period 2006-2011, in a region of southern Spain.

Results: There were 61,329 records available.

Detection of a healthy carrier of HCV with no evidence of antibodies for over four years.

Background: Posttransfusion HCV has been notably reduced over recent years as a result of the systematic testing for antibodies to HCV in blood donors. However, the risk of transfusing blood-derived components from virus-carrying donors still remains. A diagnosis is reported here of HCV in a regular blood donor who had no antibodies during the entire time she was followed up.