First Results from a Broadband Search for Dark Photon Dark Matter in the 44 to 52 μeV Range with a Coaxial Dish Antenna.

We present first results from a dark photon dark matter search in the mass range from 44 to 52  μeV (10.7-12.5 GHz) using a room-temperature dish antenna setup called GigaBREAD.

Accumulating candidate genes for broad-spectrum resistance to rice blast in a drought-tolerant rice cultivar.

Biotic stresses, including diseases, severely affect rice production, compromising producers' ability to meet increasing global consumption. Understanding quantitative responses for resistance to diverse pathogens can guide development of reliable molecular markers, which, combined with advanced backcross populations, can accelerate the production of more resistant varieties. A candidate gene (CG) approach was used to accumulate different disease QTL from Moroberekan, a blast-resistant rice variety, into Vandana, a drought-tolerant variety.

Spelling Changes and Fluorescent Tagging With Prime Editing Vectors for Plants.

Prime editing is an adaptation of the CRISPR-Cas system that uses a Cas9(H840A)-reverse transcriptase fusion and a guide RNA amended with template and primer binding site sequences to achieve RNA-templated conversion of the target DNA, allowing specified substitutions, insertions, and deletions. In the first report of prime editing in plants, a variety of edits in rice and wheat were described, including insertions up to 15 bp. Several studies in rice quickly followed, but none reported a larger insertion.

Intergenic spaces: a new frontier to improving plant health.

To more sustainably mitigate the impact of crop diseases on plant health and productivity, there is a need for broader spectrum, long-lasting resistance traits. Defense response (DR) genes, located throughout the genome, participate in cellular and system-wide defense mechanisms to stave off infection by diverse pathogens. This multigenic resistance avoids rapid evolution of a pathogen to overcome host resistance.

RNA Binding Motif Protein 48 Is Required for U12 Splicing and Maize Endosperm Differentiation.

The last eukaryotic common ancestor had two classes of introns that are still found in most eukaryotic lineages. Common U2-type and rare U12-type introns are spliced by the major and minor spliceosomes, respectively. Relatively few splicing factors have been shown to be specific to the minor spliceosome.

Maize rough endosperm3 encodes an RNA splicing factor required for endosperm cell differentiation and has a nonautonomous effect on embryo development.

Endosperm and embryo development are coordinated via epigenetic regulation and signaling between these tissues. In maize (Zea mays), the endosperm-embryo signals are not known, but endosperm cellularization is a key event for embryos to form shoots and roots. We screened seed mutants for nonautonomous functions in endosperm and embryo development with genetically nonconcordant seeds and identified the recessive mutant rough endosperm3 (rgh3).

Distributed simple sequence repeat markers for efficient mapping from maize public mutagenesis populations.

The genome sequence of the B73 maize inbred enables map-based cloning of genetic variants underlying phenotypes. In parallel to sequencing efforts, multiple public mutagenesis resources are being developed predominantly in the W22 and B73 inbreds. Efficient platforms to map mutants in these genetic backgrounds would aid molecular genetic analysis of the public resources.

Higher accumulation of F1-V fusion recombinant protein in plants after induction of protein body formation.

Improving foreign protein accumulation is crucial for enhancing the commercial success of plant-based production systems since product yields have a major influence on process economics. Cereal grain evolved to store large amounts of proteins in tightly organized aggregates. In maize, gamma-Zein is the major storage protein synthesized by the rough endoplasmic reticulum (ER) and stored in specialized organelles called protein bodies (PB).

Abdominal incisional hernia repair. Intraperitoneal prosthetic technique using Bard Kugel Composix Mesh.

The treatment of choice for incisional hernia is prosthetic repair Extensively debated issues are the materials used and the implantation site of the mesh. The authors report their personal experience with 17 cases operated on by placement of an intraperitoneal Bard Kugel Composix Mesh. From May 2003 to August 2005, 10 female and 7 male patients with incisional hernia, aged from 43 to 76 years (mean age: 65 years), were submitted to intraperitoneal prosthetic mesh implantation and monitored over a follow up period ranging from 2 to 28 months (median: 15 months).

[Incidental gallbladder carcinoma].

Carcinoma detected at histological examination of the gallbladder is defined as incidental. It is a fairly rare event, but the increase in the number of cholecystectomies performed has led to a rise in detection of incidental gallbladder carcinoma. Histologically, in most cases, these are pT1 and pT2 carcinomas.

How to improve bilio-stasis in liver surgery.

One of the most fearful complications following hepatic resection is the onset of a biliary fistula. We have attempted to improve intraoperative bilio-stasis to minimize the risk of postoperative fistula development by testing different materials. In the early 2005 we began employing a collagen sponge coated with fibrinogen and thrombin (Tachosil) In our clinical experience, prior to sponge use, a biliary fistula developed in 3.

[Solid pseudo-papillary tumor of the pancreas: a case of a big abdominal mass in a young woman].

Solid pseudo-papillary tumor of the pancreas is a rare tumor that occurs predominantly in young women. It often presents as a big abdominal mass whose preoperative diagnosis appears to be difficult. It is a low- grade malignancy tumor and surgery is the mainstay of treatment.

[Liver resection after downstaging with neoadjuvant chemotherapy for "unresectable" colorectal metastases].

Hepatic resection is the only treatment that offers a chance of long-term survival in patients with metastases from colorectal cancer. Nevertheless, a curative resection can be performed in only 10-20 per cent of patients: multiple bilobar metastases or "unresectable" disease are the greatest obstacles to surgical radicality. Techniques such as preoperative portal embolisation, preoperative portal ligation, two-stage hepatectomy, and neoadjuvant chemotherapy, have extended the possibility of liver surgery to patients with advanced metastatic colorectal cancer.

Outcome of radical surgery for carcinoma of the gallbladder according to the tumor node metastasis and Japanese Society of Biliary Surgery stages.

Primary carcinoma of the gallbladder is a progressive, lethal disease. Survival of patients with this neoplasm depends strictly on lymph node involvement and depth of tumor invasion. The aim of the study was to evaluate the results of our surgical series according to the tumor node metastasis and Japanese Society of Biliary Surgery classification systems.

[Indications and results of the first 100 liver resections in Bolzano].

The aim of the study was to report on a survey of 100 liver resections performed over an 8-year period. Seventy-four patients underwent surgery for primary or secondary liver tumours, 15 for benign diseases, and 11 for traumas. The overall operative mortality rate was 3.