Introduction: One of today's main issues is balancing work and family life, which significantly impacts the socio-economic and working conditions of the population. Since the last century, support for parenthood has been at the center of legislative attention both in Italy and Europe. The Italian Constitution of 1948 began addressing the shift from the woman's exclusively domestic role, promoting female workforce integration from the 1950s.
View Article and Find Full Text PDFBackground: COVID-19 has hit every country in the world. Almost a quarter of a billion cases and nearly 5 million deaths reported globally as of late September 2021. Compared to over 6 billion doses of COVID-19 vaccine administered, the pandemic does not seem to disappear.
View Article and Find Full Text PDFObjective: Intrathecal inflammation, compartmentalized in cerebrospinal fluid (CSF) and in meningeal infiltrates, has fundamental role in inflammation, demyelination, and neuronal injury in cerebral cortex in multiple sclerosis (MS). Since the exact link between intrathecal inflammation and mechanisms of cortical pathology remains unknown, we aimed to investigate a detailed proteomic CSF profiling which is able to reflect cortical damage in early MS.
Methods: We combined new proteomic method, TRIDENT, CSF analysis, and advanced 3T magnetic resonance imaging (MRI), in 64 MS patients at the time of diagnosis and 26 controls with other neurological disorders.