Publications by authors named "Federico Giuseppe Quarta"

Article Synopsis
  • Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare brain disorder caused by improperly folded prion proteins, with different strains linked to genetic variations and outcomes.
  • Diagnosis of sCJD typically occurs post-mortem through brain analysis, but new techniques like Real-Time Quaking-Induced Conversion (RT-QuIC) have shown prion proteins can also be found in the olfactory mucosa (OM) of living patients.
  • An optimized method called protein misfolding cyclic amplification (PMCA) successfully detected prion proteins in OM samples with high sensitivity (79.3%) and specificity (100%), although it didn't differentiate sCJD subtypes from living patients
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Objective: COVID-19 respiratory insufficiency has augmented demand of tracheostomies in intubated patients. Herein, we analyse our experience with suspension laryngoscopy-assisted percutaneous dilatational tracheostomy (SL-PDT) to assess the safety for both healthcare personnel and patients.

Methods: We conducted a retrospective review of all patients who underwent SL-PDT in the Intensive Care Unit (ICU) between March 13 and April 17, 2020 (first peak of SARS-CoV-2 pandemic).

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