Publications by authors named "Federico D Colodenco"

Article Synopsis
  • * The underlying inflammation is primarily driven by the innate and adaptive immune systems, producing cytokines (IL-4, IL-5, IL-13) that contribute to symptoms and tissue changes.
  • * New targeted therapies are emerging, based on the understanding of these pathways, providing additional options for patients not responding to standard treatments like inhaled corticosteroids.
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Introduction: The prevalence of chronic obstructive pulmonary disease (COPD) has not been studied in Argentina.

Objectives: To determine the prevalence and relevant clinical characteristics of COPD in a representative sample.

Material And Methods: We performed a cross-sectional study in a population of adults aged ≥ 40 years randomly selected by cluster sampling in 6 urban locations.

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Chronic obstructive pulmonary disease (COPD) is a multicomponent disorder that leads to substantial disability, impaired quality of life, and increased mortality. Although the majority of COPD patients are first diagnosed and treated in primary care practices, there is comparatively little information on the management of COPD patients in primary care. A web-based pilot survey was conducted to evaluate the primary care physician's, or general practitioner's (GP's), knowledge, understanding, and management of COPD in twelve territories across the Asia-Pacific region, Africa, eastern Europe, and Latin America, using a 10-minute questionnaire comprising 20 questions and translated into the native language of each participating territory.

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Background: Although several published studies have suggested that formoterol fumarate could be equivalent to short-acting beta2-agonists (SABAs) for the treatment of asthma exacerbations, its role in acute asthma treatment remains undefined.

Objective: To evaluate the efficacy and safety of inhaled formoterol (compared with SABAs) for the emergency department treatment of patients with acute asthma.

Methods: Systematic searches were conducted in MEDLINE, EMBASE, the Cochrane Controlled Trials Register, and manufactures' trial registers, without language restriction.

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