Publications by authors named "Federico D'Argenzio"

Article Synopsis
  • This study investigated how echocardiographic findings related to heart function and Troponin levels impact mortality in septic patients, focusing on those not on mechanical ventilation.
  • Out of 325 enrolled patients, those with severe sepsis and abnormal Troponin levels (Group 3) showed worse heart function and higher mortality rates compared to those with normal Troponin levels (Group 1).
  • Ultimately, while abnormal Troponin levels were linked to heart dysfunction, the presence of sepsis-induced myocardial dysfunction (SIMD) was the stronger predictor of mortality, overshadowing the role of Troponin levels.
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Article Synopsis
  • The study examined the prevalence and impact of left and right ventricular systolic dysfunction in patients with sepsis, some experiencing shock.
  • It involved 354 patients, categorized based on shock presence and lactate levels measured within 24 hours of admission.
  • Results showed that both left (LV) and right (RV) ventricular dysfunction were linked to higher mortality rates after 28 days, especially in patients without shock or with lower lactate levels.
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Background: During the initial assessment of trauma patients, the severity of injury is very often not immediately recognizable. In trauma centers, a total body CT (TBCT) scan is routinely used to evaluate this kind of patients, even if it is burdened with health risk, economical costs, and logistical difficulties.

Aim: We investigated the use of a clinical guide to establish a safe alternative to this routine practice.

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We evaluated whether in sepsis, right ventricular (RV) systolic dysfunction (RVSD) predicts short-term all-cause mortality, independently to left ventricular (LV) global longitudinal peak systolic strain (GLS). This is a prospective observational study. We enrolled 252 septic patients (40% with shock) between October 2012 and July 2018 among those admitted to High-Dependency Unit.

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