Publications by authors named "Federico Andres Colo"
Article Synopsis
- Breast cancer shows significant variation in clinical and molecular traits, making immune response a critical factor in patient outcomes, though immune prognostic markers lack full validation for clinical use.
- A study analyzed immune features in the blood of 85 nonmetastatic breast cancer patients at diagnosis, revealing increased lymphocyte counts in nonrelapsed patients and a high neutrophil-to-lymphocyte ratio linked to better disease-free survival.
- The findings support the idea of immune surveillance and suggest an "immune phenotype" that could aid in prognosis and treatment decisions for early-stage breast cancer patients.
Background: Adipose microenvironment is involved in signaling pathways that influence breast cancer. We aim to characterize factors that are modified: 1) in tumor and non tumor human breast epithelial cell lines when incubated with conditioned media (CMs) from human breast cancer adipose tissue explants (hATT) or normal breast adipose tissue explants (hATN); 2) in hATN-CMs vs hATT-CMs; 3) in the tumor associated adipocytes vs. non tumor associated adipocytes.
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