Publications by authors named "Federica Pistoni"
Article Synopsis
- Keratosis lichenoides chronica (KLC) is a rare skin condition featuring raised, rough papules that often form linear or reticular patterns, primarily affecting limbs and the trunk, with some facial involvement.
- Diagnoses are often delayed, but histological confirmation is required, and the condition affects individuals of all ages with a slight male predominance; about 25% of cases are in children.
- Current treatment options include phototherapy and systemic retinoids, which have shown effectiveness, while corticosteroids and other medications have proven ineffective.
Melanoma is characterized, among other features, by microenvironmental factors and by an altered apoptotic machinery. Melanoma cell response to a hypoxic environment is transcriptionally regulated by the Hypoxia-Inducible Factor (HIF)-1α. p75 neurotrophin receptor (p75(NTR) ), also called CD271, mediates apoptosis in several cell systems.
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