Publications by authors named "Federica Pellicori"
Article Synopsis
- The study investigates the differences in cardiovascular disease occurrence between patients with polygenic hypercholesterolemia who have high levels of Lp(a) (H-Lpa) versus those with polygenic hypercholesterolemia alone (H-LDL).
- A retrospective analysis of 258 H-Lpa patients and 290 H-LDL patients revealed that those with high Lp(a) experienced vascular events more frequently and at a younger age despite similar LDL cholesterol reductions.
- Men with H-Lpa showed a significantly higher risk of acute coronary artery disease, while women with H-Lpa faced a higher incidence of peripheral artery disease linked to smoking.
Cardiovascular disease (CVD) is still a leading cause of morbidity and mortality, despite all the progress achieved as regards to both prevention and treatment. Having high levels of lipoprotein(a) [Lp(a)] is a risk factor for cardiovascular disease that operates independently. It can increase the risk of developing cardiovascular disease even when LDL cholesterol (LDL-C) levels are within the recommended range, which is referred to as residual cardiovascular risk.
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- Hyperlipidemia significantly contributes to cardiovascular issues, and statins are the primary treatment for managing cholesterol levels and preventing heart disease.
- Patient adherence to statin therapy is often low due to side effects like statin-associated muscle symptoms (SAMS), which can range from mild pain to severe complications like rhabdomyolysis.
- Identifying SAMS is challenging as there is no standard diagnostic test, but various patient risk factors and medication interactions can heighten the likelihood of these muscle-related side effects.
To assess the usefulness of lung ultrasound (LUS) for identifying community-acquired pneumonia (CAP) among adult patients with suspected lower respiratory tract infection (LRTI) and for discriminating between CAP with different cultural statuses, etiologies, and outcomes. LUS was performed at internal medicine ward admission. The performance of chest X-ray (CXR) and LUS in diagnosing CAP in 410 patients with suspected LRTI was determined.
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