Publications by authors named "Federica Ferrod"
Article Synopsis
- The study evaluates acute normovolemic hemodilution (ANH) as a method to decrease the need for red blood cell (RBC) transfusions in patients undergoing elective cardiac surgery, aiming to reduce associated risks and costs.
- It is a randomized controlled trial conducted in various hospitals, where patients are assigned to either receive ANH before surgery or the best available alternative treatment.
- The primary goal is to see if ANH lowers the percentage of patients requiring RBC transfusion from 35% to 28%, with secondary outcomes including mortality and complications related to kidney and bleeding issues.
Background: Acute kidney injury (AKI) is a serious and common complication of cardiac surgery, for which reduced kidney perfusion is a key contributing factor. Intravenous amino acids increase kidney perfusion and recruit renal functional reserve. However, the efficacy of amino acids in reducing the occurrence of AKI after cardiac surgery is uncertain.
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