Intracochlear Position of Cochlear Implants Determined Using CT Scanning versus Fitting Levels: Higher Threshold Levels at Basal Turn.

Objectives: In this study, the effects of the intracochlear position of cochlear implants on the clinical fitting levels were analyzed.

Design: A total of 130 adult subjects who used a CII/HiRes 90K cochlear implant with a HiFocus 1/1J electrode were included in the study. The insertion angle and the distance to the modiolus of each electrode contact were determined using high-resolution CT scanning.

Population-based prediction of fitting levels for individual cochlear implant recipients.

Objectives: This study analyzed the predictability of fitting levels for cochlear implant recipients based on a review of the clinical levels of the recipients.

Design: Data containing threshold levels (T-levels) and maximum comfort levels (M-levels) for 151 adult subjects using a CII/HiRes 90K cochlear implant with a HiFocus 1/1 J electrode were used. The 10th, 25th, 50th, 75th and 90th percentiles of the T- and M-levels are reported.

Communication between human mast cells and CD4(+) T cells through antigen-dependent interactions.

Mast cells (MCs) are immune cells residing in tissues where pathogens are first encountered. It has been indicated that MCs might also be involved in setting the outcome of T-cell responses. However, little is known about the capacity of human MCs to express MHC class II and/or to capture and present antigens to CD4(+) T cells.

Effects of parameter manipulations on spread of excitation measured with electrically-evoked compound action potentials.

Objective: This study investigated the spread of excitation (SOE) profiles derived by eCAP measures and analysed the effects of various parameter settings.

Design: SOE was measured using the forward masking technique (selectivity), as well as with a "fixed stimulus, variable recording" (scanning) technique. SOE profiles were produced at three current levels and at three sites along the array.