Influence of a Novel Food-Grade Formulation of Red Chili Extract () on Overweight Subjects: Randomized, Double-Blinded, Placebo-Controlled Study.

Capsaicinoids from pungent red chilies ( and ) have received significant attention as a natural supplement for the management of obesity. However, the consumption of chili extract at physiologically relevant dosage of capsaicinoids is a challenge owing to its pungency and gastrointestinal discomforts. The present study reports the systemic absorption, safety and influence of a novel, food-grade, and sustained-release formulation of capsaicinoids-rich red chili extract using fenugreek dietary fiber (Capsifen).