Publications by authors named "Fazl M"

This study was conducted to evaluate the associations between dietary diversity score (DDS) and cardiovascular risk factors in this population. In this cross-sectional study, 187 patients, aged 18-65 years with pemphigus vulgaris were included. DDS was assessed by a 24-hour dietary recall method.

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Somatosensory evoked potentials (SSEPs) are used for neuroprognosis after severe traumatic brain injury (TBI). However decompressive craniectomy (DC), involving removal of a portion of the skull to alleviate elevated intracranial pressure, is associated with an increase in SSEP amplitude. Accordingly, SSEPs are not available for neuroprognosis over the hemisphere with DC.

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Background: Intraosseous vascular anomalies (IOVA) are rare in the craniofacial skeleton and present a diagnostic and therapeutic challenge. This study aims to describe the clinical management based on a large case series.

Methods: A retrospective chart review was performed and 9 IOVA were identified over a 15-year period.

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Acute spinal cord injury (SCI) is a major public health problem for which there is still only limited treatment available. The National Acute Spinal Cord Injury Study-2 (NASCIS-2) and -3 clinical trials demonstrated that the use of acute pharmacotherapy with methylprednisolone can attenuate the secondary injury cascade if administered within 8 hours of acute SCI. However, no trial has been performed to examine whether acute surgical decompressive procedures within this critical 8-hour time window can improve patients' neurological outcome.

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Article Synopsis
  • A 29-year-old woman experienced severe headaches, leading to a diagnosis of a brain tumor that was initially thought to be a meningioma based on radiology.
  • However, further analysis revealed the tumor was actually a primary intracranial leiomyoma, characterized by benign smooth muscle tissue.
  • Histological confirmation and additional imaging ruled out benign metastasizing leiomyoma, suggesting that leiomyoma should be considered in diagnosing similar intracranial lesions.
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Painless unilateral proptosis is a frequent manifestation of numerous orbital neoplastic and non-neoplastic processes. Various mesenchymal tumors of both fibrohistiocytic and vascular origin are well-described causes. Solitary fibrous tumors (SFTs) are rare spindle-cell neoplasms usually found associated with serosal surfaces, especially the pleura, but they have recently been described in a number of extrapleural sites including the orbit.

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Objective: Facet dislocations commonly require intraoperative reduction after closed reduction with traction has failed. Reduction should be performed in a gradual, controlled fashion to prevent additional inadvertent spinal cord compromise.

Methods: We describe a new technique for safe and simple dorsal reduction of facet dislocations by use of a modified interlaminar spreader.

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  • A clinical trial compared the effects of different durations of methylprednisolone (MP) and tirilazad mesylate (TM) on recovery after acute spinal cord injury.
  • When treatment started within 3 hours post-injury, all groups had similar recovery outcomes, but those starting treatment later performed better with a 48-hour MP regimen.
  • The study suggests that patients treated within 3 hours can use a 24-hour MP regimen, while those treated after 3 hours should receive 48 hours of therapy, unless there are complicating health issues.
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Objective: To compare the efficacy of methylprednisolone administered for 24 hours with methyprednisolone administered for 48 hours or tirilazad mesylate administered for 48 hours in patients with acute spinal cord injury.

Design: Double-blind, randomized clinical trial.

Setting: Sixteen acute spinal cord injury centers in North America.

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Direct spinal cord stimulation and recording was performed in five dogs to identify the dorsal root entry zone (DREZ) and long tracts within the dorsal and dorsolateral spinal cord using electrophysiological mapping techniques. Intrathecal recordings were obtained from sites distal to the site of stimulation. Conduction velocity in the fastest conducting fibers was higher following low-intensity stimulation of the dorsolateral spinal cord than after dorsal spinal cord stimulation.

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Article Synopsis
  • Researchers used spinal cord stimulation techniques on four patients with chronic pain from brachial plexus avulsion to pinpoint the dorsal root entry zone (DREZ).
  • Results indicated that dorsolateral stimulation of the spinal cord produced faster conduction speeds and larger evoked potential amplitudes compared to dorsal stimulation.
  • Accurate localization of the DREZ was achieved without causing neurological issues, leading to effective pain relief for all patients after the lesioning procedure.
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The purpose of this study was to evaluate the ability of posterior distraction delivered by the AO internal fixator to effect a satisfactory reduction of the intraspinal fragments in burst fractures. The overall decompression achieved was from an initial compromise of 54% to a residual encroachment of 40%. Canal clearance proved most effective when carried out in the first 4 days, with an initial canal compromise of between 34 and 66%.

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Cerebral blood flow (CBF) and central conduction time (CCT) were recorded from 58 subarachnoid hemorrhage patients and from 49 age-matched controls. CBF was calculated following Xenon inhalation and CCT was determined from somatosensory evoked potentials (SSEP's) following median nerve stimulation. Each patient had a CT scan on the day of admission which was graded from I-IV.

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The results of a consecutive series of 110 patients treated with the locking-hook spinal rod are presented. A prospective protocol was completed in 95 patients. Pain was absent or mild in 93%.

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Three patients with hyperflexion sprain of the cervical spine secondary to motor vehicle accidents are discussed. One patient exhibited tetraplegia and the other two only had paresthesia of the upper and/or lower extremities at the scene of the accident. All patients were young with no evidence of degenerative disc disease or osteoarthritis.

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A retrospective study was made of 173 cases of acute cervical spine injury with halo vest management to compare initial injury features with outcome. The object was to determine whether a mathematical model could be developed enabling a prediction to be made at the time of the initial assessment as to the probability of success or failure of conservative management using the halo vest alone, and thus perhaps avoid lengthy, unsuccessful treatment. Patients with facet joint dislocation were found to form a distinct subgroup of the injury population.

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Most vascular injuries to the brain secondary to blunt head trauma involve the internal carotid circulation. A case of isolated basilar occlusion secondary to a clival fracture is described and compared to three other cases in the literature.

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There is continuing controversy about the benefits of decompressive craniectomy in the treatment of lesions causing increased intracranial pressure (ICP) and brain edema. Laboratory work has shown a decrease in ICP after craniectomy, but also a paradoxical enhancement in the formation of underlying cerebral edema, which may act to the detriment of the patient. Since Rengachary et al.

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A technique of anterior decompression of the spinal canal with anterior strut grafts, followed by posterior instrumentation and local fusion, is described in a group of 18 patients with unstable thoracolumbar fractures. All patients were found to have greater than 50% encroachment of the spinal canal and a preoperative kyphosis of 21.8 degrees.

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Sixty consecutive patients with spinal injuries and encroachment upon the spinal canal of greater than 20% were assessed for neurological outcome. The patients were divided into two groups, those undergoing posterior surgery alone, and those undergoing anterior surgery for formal decompression with or without anterior or posterior instrumentation. In those patients undergoing posterior surgery, an improvement rate in the neurological function of 83% was noted in patients with incomplete lesions, whereas an 88% improvement rate was found in those undergoing the anterior procedure.

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The radiological findings in 10 patients with sacral cysts were retrospectively reviewed and classified. The cysts were an incidental finding on computed tomography (CT) in four patients. The expansion of sacral foramina or the sacral canal as seen on plain films suggested the diagnosis in three.

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