Chronic kidney disease after heart transplantation.

Background: Chronic kidney disease (CKD) is a complication of heart transplantation related to calcineurin inhibitor nephrotoxicity. However, it is unclear whether early ciclosporin (CsA) exposure influences CKD in the long term.

Methods: We analysed risk factors for CKD in 352 patients who underwent orthotopic heart transplantation (1995-2005).