Efficacy and side effects of glyceryl trinitrate in management of chronic anal fissure.

Background: Various options are available for treatment of chronic anal fissure, each with its own associated complications. This study aimed to evaluate the efficacy of topical Glyceryl Trinitrate (GTN) for anal fissures in an outpatient setting.

Methods: A prospective experimental study was carried out at the outpatient department of Surgical Unit IV, Liaquat University Hospital from Aug 2004 to Jul 2005.

Diltiazem (2%) versus glyceryl trinitrate cream (0.2%) in the management of chronic anal fissure.

Objective: To assess and compare the effectiveness of topical 0.2% glycerl trinitrate (GTN) and topical 2% diltiazem (DTZ), in the management of chronic anal fissure.

Study Design: Comparative, descriptive study.

Open excision with secondary healing versus rhomboid excision with Limberg transposition flap in the management of sacrococcygeal pilonidal disease.

Objective: To compare the outcome of Open excision and secondary healing with rhomboid excision and Limberg flap in the management of sacrococcygeal pilonidal sinus disease (SPD).

Methods: A prospective, analytical, comparative study using randomized controlled trial (RCT) was conducted at Liaquat University Hospital (Jamshoro) & Fatima Hospital-Baqai Medical University (Karachi), from June 2004 to July 2007. In total 49 patients, who either underwent open excision and secondary healing (group A: 25 patients) or rhomboid excision and Limberg flap (group B: 24 patients), were enrolled in the study.

Serum creatine phosphokinase as prognostic indicator in the management of electrical burn.

Objective: To determine the mean difference of serum creatine phosphokinase according to the extent of tissue damage and prognosis of the patients suffering from electrical burn injuries.

Study Design: A case series study.

Place And Duration Of Study: Department of Burns, Liaquat University Hospital, Hyderabad, from September 2005 to August 2006.

Extra-biliary complications during laparoscopic cholecystectomy: How serious is the problem?

Objective: To deteremine the incidence, nature and management of extra-biliary complications of laparoscopic cholecystectomy.

Materials And Methods: This study presents a retrospective analysis of extra-biliary complications occuring during 1046 laparoscopic cholecystectomies performed from August 2003 to December 2006. The study population included all the patients with symptomatic gallstone disease in whom laparoscopic cholecystectomy was performed.