Publications by authors named "Fazhuang Fang"

In order to explore the relationship between GSTM1 and GSTT1 gene polymorphisms and gallbladder cancer, so as to find a better treatment and prevention of gallbladder cancer and improve the treatment effect. In this paper, 247 patients with gallbladder cancer were selected for the experiment, including 187 male patients and 60 female patients. The total number of patients was randomly divided into two groups, namely the case group and the control group.

View Article and Find Full Text PDF

Objective: Colon cancer (CC) is the third most common cancer with a high rate of incidence and mortality. Therefore, it is highly necessary to explore novel targets of CC.

Methods: The miRNA-seq and RNA-seq data of CC were accessed from the TCGA database.

View Article and Find Full Text PDF

Objective: The Grainyhead-like (GRHL) genes family were reported to participate in the development of a number of diseases. This study was designed to investigate the role of genes family in colon cancer (CC).

Methods: In this study, the transcriptional levels of genes family in patients with CC from GEPIA were explored.

View Article and Find Full Text PDF

Synopsis of recent research by authors named "Fazhuang Fang"

  • - Fazhuang Fang's research primarily focuses on the genetic factors associated with cancer, emphasizing polymorphisms in genes related to gallbladder and colon cancers, with an aim to enhance treatment and prevention strategies.
  • - In a 2022 study, Fang investigated the relationship between GSTM1 and GSTT1 gene polymorphisms and gallbladder carcinoma, analyzing 247 patients to potentially improve treatment outcomes for this cancer type.
  • - Another notable contribution is exploring the role of the Grainyhead-like genes family as potential biomarkers in colon cancer, as well as identifying novel targets for colon cancer therapies through RNA sequencing methods, reflecting a commitment to addressing significant cancer research challenges.