Relationship between Nutrition, Lifestyle Habits and Laboratory Parameters in Hypertensive Patients with/without Cognitive Dysfunction.

Unlabelled: (1) Background: Cognitive dysfunction is a major concern in hypertensive patients. Lifestyle habits and nutrition influence laboratory parameters, with an impact on clinical course. The objective of the study was to evaluate nutrition and lifestyle habits in hypertensive patients with/without cognitive dysfunction and establish correlations to laboratory parameters.

[Quality of life of consumers following a gluten-free diet. ].

With the rising consumer's health awareness, especially towards patients with celiac disease, gluten has become a food ingredient to be avoided by many people expecting various positive health effects. The strict adherence of diet requires serious abandonments and lifestyle changes that affect directly their quality of life. The aim of the present study was to recognise the quality of life of Hungarian and Romanian consumers following a gluten-free diet as well as to explore the negative effects on them.

Knowledge about sources of dietary fibres and health effects using a validated scale: a cross-country study.

Objectives: Dietary fibre (DF) is one of the components of diet that strongly contributes to health improvements, particularly on the gastrointestinal system. Hence, this work intended to evaluate the relations between some sociodemographic variables such as age, gender, level of education, living environment or country on the levels of knowledge about dietary fibre (KADF), its sources and its effects on human health, using a validated scale.

Study Design: The present study was a cross-sectional study.

Knowledge about dietary fibres (KADF): development and validation of an evaluation instrument through structural equation modelling (SEM).

Objectives: Because there is scientific evidence that an appropriate intake of dietary fibre should be part of a healthy diet, given its importance in promoting health, the present study aimed to develop and validate an instrument to evaluate the knowledge of the general population about dietary fibres.

Study Design: The present study was a cross sectional study.

Methods: The methodological study of psychometric validation was conducted with 6010 participants, residing in 10 countries from three continents.

Smoking habits of pharmacy students attending the University of Medicine and Pharmacy in Targu Mures.

Unlabelled: Smoking is common among health professional students. The aim of this study was to assess the smoking habits of the pharmacy students attending the University of Medicine and Pharmacy in Târgu Mureș (UMPh TM), Romania.

Material And Methods: Smoking habits and attitudes toward smoking among 414 pharmacy students attending UMPh TM (86% female) were evaluated using a self-completed questionnaire.

Intraoral fluoride levels after use of conventional and high-fluoride dentifrices.

Objectives: This study aimed to evaluate saliva and plaque as indicators of intraoral fluoride (F) levels after the use of conventional and high-fluoride dentifrices.

Materials And Methods: Subjects were randomly assigned to brush their teeth with conventional (1000 ppm F), high-fluoride (5000 ppm F), and placebo dentifrices (fluoride free) for 10 days, following a double-blind, crossover protocol. Saliva and plaque samples were collected on the morning of the 5(th) and 10th days, respectively at 1 and 12 h after brushing, and analyzed with an ion-selective electrode after HMDS-facilitated diffusion.

A comparison of two methods for the evaluation of the daily urinary fluoride excretion in Romanian pre-school children.

Objective: To compare two different methods of estimating daily fluoride urinary excretion in pre-school children under stable fluoride intake conditions.

Design: Thirty-five healthy kindergarten children, permanent residents of Targu-Mures, Romania, where the average drinking water fluoride concentration is 0.12 mg F/L, participated on two separate occasions, when they were aged 4-6 and 5-7 years, respectively in the collection of a) a mid-morning spot urine sample and b) a 16-h time-controlled urine sampling.

Changes in the central nervous activity of rats treated with dimethoate in combination with other neurotoxicants in different phases of ontogenesis.

Organophosphates are usually found in the environment with other pesticides and with pollutants of industrial origin can cause combined exposure involving unknown interactions between the agents. In this study, female Wistar rats were given 1/25 LD50 of dimethoate by gavage, combined with the same LD50 fractions of propoxur and cypermethrin or with arsenic (6.66 mg kg(-1)).

Combined effects of subchronic exposure to lead, mercury and alcohol on the spontaneous and evoked cortical activity in rats.

The aim of this study was to investigate the effects of a combination of well-known neurotoxic heavy metals, lead and mercury, with ethanol. For 12 weeks, young adult male Wistar rats were given plain tap water or water containing 5% (v/v) ethanol to drink, and were treated with two doses of lead acetate or mercuric chloride by gavage. Accordingly, there was a water-drinking and an alcohol-drinking control group.

[Severe necrotic processes of the penis and scrotum].

Authors summarise the two-decade experience of their department in severe tissue necrosis of penis and scrotum. Presented cases represent a shared field of urology with dermatology, infectology, nephrology and andrology. Tissue necrosis extended to different depth of the penis, from superficial skin and subcutaneous tissues, fascias to the entire organ.

Role of alphaII(b)beta3 integrin in prostate cancer metastasis.

Background: Integrins participate in cell-cell and cell-matrix interactions. In this study we determined whether alphaII(b)beta3 integrin is involved in metastasis of human prostate adenocarcinoma cells.

Methods: Prostate adenocarcinoma PC-3 and DU-145 cell lines express alphaII(b)beta3.

Multiple use of a signal transduction pathway in tumor cell invasion.

Recent reports have indicated that a poorly characterized signaling pathway involving 12-lipoxygenase and PKC is involved in several steps of the metastatic cascade such as tumor cell adhesion to matrix, lysosomal enzyme release and migration. We investigated here the upstream elements of this signalling pathway looking for receptors which it might be coupled to. We described tumor cell alpha IIb beta 3-like integrin and the AMF receptor, gp78, as two transmembrane receptors which utilize the 12-lipoxygenase/PKC signaling.