The reuse and development of natural waste resources is a hotspots and challenges in the research of new fiber materials and the resolution of environmental concern globally. Herein, this study aimed to develop a simple and direct manual extraction process to extract Musa core fibers (MCFs) for rapid water conduction and evaporation. Through simple processes such as ring cutting and stretching, this green and non-destructive inside-out extraction strategy enabled Musa fibers to be naturally and harmlessly degummed from natural Musa stems, with good maintenance of the fiber structure and highly helical morphology.
View Article and Find Full Text PDFTiO has been widely used in photodegradation of pollutants, but it suffers from inferior photocatalytic performance under solar light illumination. Thus, novel porous ZnTiO/TiO heterostructured photocatalysts are constructed by hydrothermal and carbonization techniques using ZIF-8 as a sacrificial template. After coating with TiO, ZIF-8 nanocubes are selectively etched and subsequently coprecipitated with Ti ions during the hydrothermal process.
View Article and Find Full Text PDFBackground: Asporin (ASPN) has been identified as a player in tumorigenesis, but its precise roles and modulatory function are largely unknown.
Methods: In the present study, ASPN expression was first explored, followed by a prognostic evaluation of ASPN and a comprehensive investigation of the connections between ASPN and immunomodulation, immune cell infiltration and potential compounds on a pancancer level. Finally, ASPN expression was validated in bladder urothelial carcinoma (BLCA) tissues, and the potential function of ASPN, including its effects on migration and invasion capabilities, was investigated in tumor cells.
Myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs), two immunosuppressive myeloid components within the tumor microenvironment (TME), represent fundamental barriers in cancer immunotherapy, whereas current nanomedicines rarely exert dual modulatory roles on these cell types simultaneously. Reactive oxygen species (ROS) not only mediates MDSC-induced immunosuppression but also triggers differentiation and polarization of M2-TAMs. Herein, an ROS scavenging nanozyme, Zr-CeO, with enhanced superoxide dismutase- and catalase-like activities for renal tumor growth inhibition is reported.
View Article and Find Full Text PDFObjectives: To analyze the correlations between the expression and effect of DNA damage repair genes and the immune status and clinical outcomes of urothelial bladder cancer (BLCA) patients. In addition, we evaluate the efficacy and value of utilizing the DNA damage repair genes signature as a prognosis model for BLCA.
Methods: Two subtype groups (C1 and C2) were produced based on the varied expression of DNA damage repair genes.
Objectives: Exosomes are essential mediators of intercellular communication as they transport proteins and RNAs between cells. Owing to their tumor-targeting capacity, immune compatibility, low toxicity, and long half-life, mesenchymal stem cell-derived exosomes have great potential for the development of novel antitumor strategies. In this context, the role of exosomes produced by adipose-derived mesenchymal stem cells (ADSCs) for the treatment of bladder cancer (BC) remains unclear.
View Article and Find Full Text PDFCancer metastasis, a typical malignant biological behavior involving the distant migration of tumor cells from the primary site to other organs, contributed majorly to cancer-related deaths of patients. Although constant efforts have been paid by researchers to elucidate the mechanisms of cancer metastasis, we are still far away from the definite answer. Recently, emerging evidence demonstrated that cancer metastasis is a continuous coevolutionary process mediated by the interactions between tumor cells and the host organ microenvironment, and epigenetic reprogramming of metastatic cancer cells may confer them with stronger metastatic capacities.
View Article and Find Full Text PDFPolyoxymethylene (POM) fiber was treated with atmospheric dielectric barrier discharge (DBD) plasma to enhance the surface activity of the fiber and interfacial interaction with cement. The physical and chemical properties of samples with different DBD plasma treatment durations were tested and analyzed. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) revealed that the surface roughness of the sample increased significantly as a result of the DBD plasma treatment.
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