Reasons for rarity of anal melanocytic naevi.

In the last 16 years only seven definite cases of anal melanocytic naevi have been reported in the literature. We describe three new cases, none of which were suspected clinically and were incidentally diagnosed on histological examination of haemorrhoidectomy specimens. The infrequency of these special site flexural melanocytic lesions may be related to changes in the involutionary mechanisms of the anal melanocyte proliferation.

Merkel Cell Carcinoma Arising in an Epidermal Cyst.

Merkel cell carcinoma is a rare aggressive primary cutaneous neuroendocrine tumor. It is associated mostly with malignant skin lesions. Rare cases in the literature described its association with benign skin adnexal lesions.

Spectrum of malignant lymphomas in Bahrain. Leitmotif of a regional pattern.

Objective: To determine the clinicopathologic features of malignant lymphomas in Bahraini patients.

Methods: A retrospective hospital-based study was conducted. All new cases of malignant lymphoma diagnosed during the period January 1996 to December 2001 at the Salmaniya Medical Complex in Bahrain were included in the study.

The pathological expressions of Brunners gland hyperplasia into adenoma and hamartoma.

The terms Brunners gland adenoma and hamartoma are 2 pathological expressions of hyperplasia of these glands. We report 3 patients and review the recent literature to support our hypothesis of common pathology. Awareness of the existence and character of Brunners gland lesions will increase the possibility of their accurate diagnosis.