Publications by authors named "Faye Zhao"
Article Synopsis
- * The trial included 28 patients and showed promising results with an overall response rate of 82%, and a complete response rate of 71%, especially in a subgroup treated with a low dosage of CAR T cells (25×10).
- * With a median follow-up of 24 months, the therapy demonstrated a 1-year event-free survival rate of 61%, while serious side effects were relatively low, indicating the potential for this approach in treating
J Am Heart Assoc
July 2024
Article Synopsis
- Researchers studied serum levels of 4123 proteins in 1117 patients with heart failure with preserved ejection fraction (HFpEF) to identify prognostic markers linked to clinical outcomes.
- A total of 288 proteins were found to be significantly associated with heart failure hospitalization and cardiovascular death, with specific proteins like B2M and TIMP1 showing strong correlations.
- The study concluded that the protein markers for HFpEF are similar to those for heart failure with reduced ejection fraction, implying that the derived proteomic risk scores do not offer improved predictive power for HFpEF patients.
ESC Heart Fail
December 2021
Article Synopsis
- The HERMES consortium is focused on understanding the genomic and molecular factors that contribute to heart failure by analyzing data from a large number of studies worldwide.
- It includes 51 studies from 11 countries, gathering data from over 68,000 heart failure cases and nearly 950,000 controls, with broad demographic representation and long follow-up periods.
- The main goals are to identify genetic risk factors for heart failure, explore causal pathways, and create tools to help stratify patients and predict risks based on their genetic information.
