Risk factors for abnormal anal cytology over time in HIV-infected women.

Objective: The objective of the study was to assess the incidence of, and risk factors for, abnormal anal cytology and anal intraepithelial neoplasia (AIN) 2-3 in human immunodeficiency virus (HIV)-infected women.

Study Design: This prospective study assessed 100 HIV-infected women with anal and cervical specimens for cytology and high-risk human papillomavirus (HPV) testing over 3 semiannual visits.

Results: Thirty-three women were diagnosed with an anal cytologic abnormality at least once.