Front Biosci
January 1998
Rotavirus gastroenteritis is one of the main causes of acute diarrhea in young humans and animals worldwide. The colostrum-deprived, artificially-reared, neonatal pig has been extensively used in our laboratory as a model animal for studying an experimentally-induced rotaviral gastroenteritis. Details on procurement of newborn pigs, immunological characteristics and artificial rearing conditions of colostrum-deprived neonatal pigs as well as on rotavirus inoculation, clinical manifestations and evaluation of intestinal damage caused by rotavirus infection are described.
View Article and Find Full Text PDF