Publications by authors named "Faxian Yi"
Article Synopsis
- - Neuroendocrine prostate neoplasms are rare types of prostate tumors, with large cell neuroendocrine prostate cancer (LCNEPC) being particularly uncommon, as highlighted in the report of a patient who experienced both severe urinary issues and elevated PSA levels.
- - After being diagnosed with adenocarcinoma through imaging and biopsy, the patient underwent lung tumor resection revealing both primary lung cancer and metastatic prostate cancer, followed by several treatments including endocrine therapy and radical prostatectomy.
- - Unfortunately, despite treatment, the patient's condition deteriorated with multiple metastases leading to multi-organ failure from chemotherapy side effects, emphasizing the need for improved management approaches for rare cases like LCNEPC.
Background: To explore the role of long noncoding RNAs (lncRNAs) cytoskeleton regulator RNA (CYTOR) in renal cell carcinoma (RCC).
Methods: The levels of CYTOR in RCC tissues and cell lines were detected by RT-qPCR. 786-O and Caki-1 cells were transfected with CYTOR-shRNA or pcDNA-CYTOR respectively, or co-transfected with CYTOR-shRNA and miR-136-5p inhibitor, or co-transfected with miR-136-5p mimic and pcDNA-MAT2B.
Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, and has become an important global burden of disease. Transurethral plasmakinetic resection of prostate (TUPKP) is one of the foremost surgical procedures for the treatment of BPH. It has become well established in clinical practice with good efficacy and safety.
View Article and Find Full Text PDFAberrant expression of miR‑154 is usually found in cancer studies; however, the role of miR‑154 has seldom been reported in bladder cancer (BCa). In this study, we observed that miR‑154 expression was significantly downregulated in BCa tissues and cell lines, and was associated with several clinicopathological characteristics, including advanced T stage, lymphatic invasion, and distant metastasis. Low expression level of miR‑154 was associated with poor survival outcomes in BCa patients.
View Article and Find Full Text PDFBackground: It has been reported that the hypermethylation of APAF-1, DAPK-1 and other tumor suppressive genes (TSGs) correlates with progression of renal cell carcinoma and exerts prognostic and diagnostic relevance in renal cell carcinoma. A recent study has confirmed that demethylation regulates the TSGs expression and proliferation of various types of cancer cells. The present study was to recognize a potential anti-tumor effect of 5-aza-2'-deoxycytidine (DAC), a demethylation agent.
View Article and Find Full Text PDF[Relationship between TMPRSS2: ERG and the pathological grade of prostate cancer].
Zhonghua Nan Ke Xue
October 2015
Objective: To study the relationship between TMPRSS2: ERG gene fusion and the pathological grade of prostate cancer (PCa).
Methods: We collected fresh prostatic tissue samples from 62 patients with PCa and another 10 with benign prostatic hyperplasia ( BPH) and included 9 cancer cell strains as the control. We examined the TMPRSS2:ERG fusion gene in the PCa samples by nest RT-PCR, compared the Gleason scores between the TMPRSS2:ERG-positive and -negative cases, and analyzed the association of TMPRSS2: ERG fusion with the pathological features of PCa.
Risk factors for prostatic inflammation extent and infection in benign prostatic hyperplasia.
Asian J Androl
September 2006
Aim: To investigate the risk factors for prostatic inflammation extent and infection in patients with benign prostatic hyperplasia (BPH) so as to manage prostatic inflammation more efficiently.
Methods: Sixty patients with BPH undergoing TURP between September 2005 and December 2005 in West China Hospital of Sichuan University were studied. Prostate fluid (PF) was collected for the measurement of secretory IgA (SIgA) and complement 3 (C3).