Publications by authors named "Fawzi Addad"
Article Synopsis
- - Recent research found that certain genetic markers in the renin angiotensin system may impact the likelihood of developing coronary artery disease (CAD), particularly in the Tunisian population.
- - A study involving 341 CAD patients and 316 healthy controls showed significant differences in the distribution of specific genetic polymorphisms (like ACE Ins/Del and angiotensinogen T174M and M235T) between the two groups, suggesting a higher risk for those with specific genotypes.
- - In conclusion, the presence of the Ins/Del, M235T, and T174M polymorphisms, along with factors like body mass index and cholesterol levels, were linked to an increased risk of CAD, while the A1166
Background: Myocardial infarction (MI) is induced by acquired and inherited risk factors, including the plasminogen activator inhibitor-1 (PAI-1) -844G/A and -675G/A (4G/5G) gene variants.
Objective: The aim of this study was to investigate the association between PAI-1-844G/A and 4G/5G polymorphisms and changes in PAI-1 and tissue plasminogen activator (tPA) levels in MI in a Tunisian population.
Methods: This was a case-control study involving 305 patients with MI and 328 unrelated healthy controls.