Cilengitide Inhibits Neovascularization in a Rabbit Abdominal Aortic Plaque Model by Impairing the VEGF Signaling.

Background: Cilengitide is a selective and integrin inhibitor. We sought to investigate the effect of cilengitide on the neovascularization of abdominal aortic plaques in rabbits and explore its underlying antiangiogenic mechanism on human umbilical vein endothelial cells (HUVECs).

Materials And Methods: For the experiment, the abdominal aortic plaque model of rabbits was established and injected with different doses of cilengitide or saline for 14 consecutive days.

Shear Behaviors of RC Beams Externally Strengthened with Engineered Cementitious Composite Layers.

The shear behaviors of reinforced concrete (RC) beams externally strengthened with engineered cementitious composite (ECC) layers were studied and the strengthening effect was evaluated based on a truss and arch model. The beams were designed without web reinforcement in the middle part and ECC was sprayed onto both sides of the beams to the designed thicknesses, which were 20 mm and 40 mm. A series of four-point bending experiments were conducted and analyzed.

Isolated right ventricular hypoplasia caused by giant aneurysm of right coronary artery to left ventricle fistula in an adult: a case report.

Background: Right ventricular hypoplasia (RVH) is often caused by tricuspid valve atresia and pulmonary valve atresia. this condition leads to low right ventricular blood volume and right ventricular maldevelopment. But, in adults, the main cause of RVH may also be associated with alloplasia of the right coronary artery, which results in an insufficient blood supply to the right ventricular myocardium.

[Evaluation of left ventricular systolic asynchrony in patients with uremic myocardiopathy using tissue synchronization imaging].

Objective: To evaluate the left ventricular systolic asynchrony in patients with uremic myocardiopathy (UM) using tissue synchronization imaging (TSI).

Methods: Ultrasound system with TSI and Q-analyze software were used. Thirty-five patients with UM were enrolled in the study,and thirty normal subjects were included as the control group.